http://hdl.handle.net/2440/50927 2013-05-18T14:42:07Z 2013-05-18T14:42:07Z Andrew, Nicholas Howard Kearney, Daniel John Selva-Nayagam, Dinesh Niranjan http://hdl.handle.net/2440/77705 2013-05-14T03:30:17Z 2011-12-31T13:30:00Z

Title: IgG4-related orbital disease: a meta-analysis and review Author: Andrew, Nicholas Howard; Kearney, Daniel John; Selva-Nayagam, Dinesh Niranjan Abstract: IgG4-related orbital disease (IgG4-ROD) is a recently described condition that may account for a significant proportion of idiopathic lymphoplasmacytic or sclerotic orbital lesions. This study is the first meta-analysis of published cases and reveals several differences between IgG4-related disease affecting the orbit and that affecting the pancreas. IgG4-ROD affects a slightly younger group of patients, affects men and women approximately equally, is commonly associated with salivary gland lesions, is associated with a relatively higher serum IgG4 and may confer an increased risk of non-Hodgkin Lymphoma. Its pathogenesis may involve an immune response to antigen exposure in the upper aerodigestive tract.

2011-12-31T13:30:00Z Gao, Zoe Weizhi Crompton, John Lionel http://hdl.handle.net/2440/77662 2013-05-13T05:30:31Z 2011-12-31T13:30:00Z

Title: Horner Syndrome: a practical approach to investigation and management Author: Gao, Zoe Weizhi; Crompton, John Lionel

2011-12-31T13:30:00Z Casson, Robert James Raymond, Grant Leslie Newland, Henry Simpson Gilhotra, Jagjit Singh Gray, Timothy Lewis http://hdl.handle.net/2440/77463 2013-05-07T03:30:19Z 2011-12-31T13:30:00Z

Title: Pilot randomized trial of a nanopulse retinal laser versus conventional photocoagulation for the treatment of diabetic macular oedema Author: Casson, Robert James; Raymond, Grant Leslie; Newland, Henry Simpson; Gilhotra, Jagjit Singh; Gray, Timothy Lewis

2011-12-31T13:30:00Z Sia, Ik Tuo Chan, WengOnn Wormald, Peter-John Davis, Gary John Selva-Nayagam, Dinesh Niranjan http://hdl.handle.net/2440/77440 2013-05-07T00:30:11Z 2011-12-31T13:30:00Z

Title: Decompression of benign orbital apex lesion via medial endoscopic approach Author: Sia, Ik Tuo; Chan, WengOnn; Wormald, Peter-John; Davis, Gary John; Selva-Nayagam, Dinesh Niranjan Abstract: The use of endoscopic orbital and optic nerve decompression for traumatic optic neuropathy and dysthyroid orbitopathy have been well documented; however, reports on endoscopic decompression for benign orbital apex lesions are scarce. The records of two patients who underwent endoscopic decompression of the bony orbit for progressive visual loss were reviewed. Patient 1 had fibrous dysplasia and presented with headache and visual field defects. Patient 2 had sphenoid wing meningioma and multiple previous attempts of transcranial tumor resection and orbital decompression. Both had progressive visual deterioration and ultimately underwent transnasal endoscopic orbital decompression. Post-operatively, both patients had subjective and objective improvement in visual function and compressive symptoms. No complications from the endoscopic decompression were observed in both patients. Transnasal endoscopic approach may be a viable option for decompression of benign orbital apex lesions.

2011-12-31T13:30:00Z