http://hdl.handle.net/2440/1091 Search the Channel search http://digital.library.adelaide.edu.au/dspace/simple-search http://hdl.handle.net/2440/53723 Title: Basal and angiopoietin-1-mediated endothelial permeability is regulated by sphingosine kinase-1 <br/> <br/>Author: Li, Xiaochun; Stankovic, Milena; Bonder, Claudine Sharon; Hahn, Christopher Norman; Parsons, Michelle; Pitson, Stuart Maxwell; Xia, Pu; Proia, Richard L.; Vadas, Mathew; Gamble, Jennifer Ruth <br/> <br/>Description: Copyright © 2008 by American Society of Hematology http://hdl.handle.net/2440/53722 Title: Rapid identification and differentiation of Ttichophyton species, based on sequence Polymorphisms of the ribosomal internal transcribed spleacer regions, by rolling-circle amplification <br/> <br/>Author: Kong, Fanrong; Tong, Zhongsheng; Chen, Xiaoyou; Sorrell, T. C.; Wang, B.; Wu, Qixuan; Ellis, David Hedley; Chen, S. <br/> <br/>Abstract: DNA sequencing analyses have demonstrated relatively limited polymorphisms within the fungal internal transcribed spacer (ITS) regions among Trichophyton spp. We sequenced the ITS region (ITS1, 5.8S, and ITS2) for 42 dermatophytes belonging to seven species (Trichophyton rubrum, T. mentagrophytes, T. soudanense, T. tonsurans, Epidermophyton floccosum, Microsporum canis, and M. gypseum) and developed a novel padlock probe and rolling-circle amplification (RCA)-based method for identification of single nucleotide polymorphisms (SNPs) that could be exploited to differentiate between Trichophyton spp. Sequencing results demonstrated intraspecies genetic variation for T. tonsurans, T. mentagrophytes, and T. soudanense but not T. rubrum. Signature sets of SNPs between T. rubrum and T. soudanense (4-bp difference) and T. violaceum and T. soudanense (3-bp difference) were identified. The RCA assay correctly identified five Trichophyton species. Although the use of two "group-specific" probes targeting both the ITS1 and the ITS2 regions were required to identify T. soudanense, the other species were identified by single ITS1- or ITS2-targeted species-specific probes. There was good agreement between ITS sequencing and the RCA assay. Despite limited genetic variation between Trichophyton spp., the sensitive, specific RCA-based SNP detection assay showed potential as a simple, reproducible method for the rapid (2-h) identification of Trichophyton spp. <br/> <br/>Description: Copyright © 2008, American Society for Microbiology. All Rights Reserved. http://hdl.handle.net/2440/53721 Title: Upper airway surface tension but not upper airway collapsibility is elevated in primary Sjogren's syndrome <br/> <br/>Author: Hilditch, Cassie Jade; McEvoy, Ronald Douglas; George, Kate E.; Thompson, Courtney; Ryan, Melissa K.; Rischmueller, Maureen; Catcheside, Peter http://hdl.handle.net/2440/53632 Title: Dasatinib suppresses in vitro natural killer cell cytotoxicity <br/> <br/>Author: Blake, Stephen James Palmer; Lyons, Alan Bruce; Fraser, Cara Kate; Hayball, John Dominic; Hughes, Timothy Peter