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Adelaide Research and Scholarship
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Schools and Disciplines
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School of Medicine
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Surgery
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Surgery Publications
Permanent link to this item:
http://hdl.handle.net/2440/52140
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| Type: | Article |
| Title: | Esophageal pH profile following laparoscopic total fundoplication compared to anterior fundoplication |
| Author: | Wong, Andrew
Myers, Jennifer Clare
Jamieson, Glyn Garfield |
| Citation: | Journal of Gastrointestinal Surgery, 2008; 12 (8):1341-1345 |
| Publisher: | Springer |
| Issue Date: | 2008 |
| ISSN: | 1091-255X |
| School/Discipline: | School of Medicine : Surgery |
Statement of
Responsibility: | Andrew S. Y. Wong, Jennifer C. Myers and Glyn G. Jamieson |
| Abstract: | In Barrett’s esophagus, total abolition of reflux may give maximum protection against the development of malignancy. To determine whether laparoscopic anterior fundoplication gives the same degree of antireflux control as a total fundoplication, we analyzed a prospectively followed cohort of patients from randomized controlled trials of laparoscopic antireflux surgery. There were 167 patients who returned for routine esophageal pH studies within 6 months of surgery (123 laparoscopic total fundoplications and 44 anterior fundoplications). There was no difference in percentage time pH <4 between fundoplication groups, but the total number of reflux episodes was significantly different (total fundoplication, four reflux events vs. partial fundoplication, six reflux events; p = 0.03). It is difficult to believe that this difference is either biologically or clinically important. In patients with a second esophageal pH study more than 5 years later, both the percentage time pH <4 (0.1% total fundoplication vs. 2.7% partial fundoplication; p = 0.004) and total number of reflux episodes (three total fundoplication vs. 24 partial fundoplication; p = 0.002) were significantly different. However, the postoperative esophageal acid exposure was within the normal range for both total and partial fundoplication, so whether the statistical difference is clinically important, remains a moot point. |
| Keywords: | Laparoscopic fundoplication; Gastro-esophageal reflux; Esophageal pH monitoring; Randomized controlled trial |
| Description: | The original publication can be found at www.springerlink.com |
| RMID: | 0020081788 |
| DOI: | 10.1007/s11605-008-0486-y |
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| Appears in Collections: | Surgery Publications
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