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https://hdl.handle.net/2440/54781
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Type: | Journal article |
Title: | Uterine leiomyoma and menstrual cycle characteristics in a population-based cohort study |
Author: | Marino, J. Eskenazi, B. Warner, M. Samuels, S. Vercellini, P. Gavoni, N. Olive, D. |
Citation: | Human Reproduction, 2004; 19(10):2350-2355 |
Publisher: | Oxford Univ Press |
Issue Date: | 2004 |
ISSN: | 0268-1161 1460-2350 |
Statement of Responsibility: | J.L. Marino, B. Eskenazi, M. Warner, S. Samuels, P. Vercellini, N. Gavoni and D. Olive |
Abstract: | BACKGROUND: We examined the association of uterine leiomyoma with menstrual cycle characteristics in a population of non-care-seeking women. METHODS: This cross-sectional study uses data from the Seveso Women's Health Study (SWHS), a population-based cohort in Italy. Participants included 341 premenopausal women, 30–60 years old, who had an intact uterus and were not pregnant, lactating, or using oral contraception or intra-uterine devices. We examined the presence of any ultrasound-detected uterine leiomyoma in relation to self-reported menstrual cycle length, flow length and heaviness of flow. The association of leiomyoma number, volume, tissue layer location and axial position with menstrual cycle characteristics was also examined. RESULTS: Uterine leiomyomata were detected in 73 women (21.4%). After adjustment for covariates, the presence of a leiomyoma was not significantly related to menstrual cycle length, flow length or heaviness of flow [odds ratio (OR) for scanty flow =1.9, 95% confidence interval (CI) 0.8–4.3; OR for heavy flow =1.3, 95% CI 0.7–2.5; relative to moderate flow]. Number, volume, tissue layer location (subserosal or intramural) and axial position (anterior or posterior) of the leiomyoma were also not related to menstrual cycle characteristics. CONCLUSION: In this Italian population of women not seeking gynaecological care, menstrual characteristics are not related to leiomyoma. |
Keywords: | epidemiology leiomyoma menstrual cycle transvaginal ultrasound |
DOI: | 10.1093/humrep/deh407 |
Published version: | http://dx.doi.org/10.1093/humrep/deh407 |
Appears in Collections: | Aurora harvest 5 Obstetrics and Gynaecology publications |
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