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Type: Journal article
Title: New cylindrical peptide assemblies defined by extended parallel β-sheets
Other Titles: New cylindrical peptide assemblies defined by extended parallel beta-sheets
Author: Pehere, Ashok D.
Sumby, Christopher James
Abell, Andrew David
Citation: Organic & Biomolecular Chemistry, 2013; 11(3):425-429
Publisher: Royal Society of Chemistry
Issue Date: 2013
School/Discipline: School of Chemistry and Physics : Chemistry
Statement of
Ashok D. Pehere, Christopher J. Sumby and Andrew D. Abell
Abstract: A new approach to non-covalent peptide-based nanotubular or rod-like structures is presented, whereby the monomeric units are preorganised into a β-strand geometry that templates the formation of an extended and unusual parallel β-sheet rod-like structure. The conformational constraint is introduced by Huisgen cycloaddition to give a triazole-based macrocycle, with the resulting self-assembled structures stabilized by a well-defined series of intermolecular hydrogen bonds.
Description: Received 17 Aug 2012, Accepted 25 Sep 2012, First published on the web 26 Sep 2012 (from RCS website)
Rights: © The Royal Society of Chemistry
RMID: 0020123522
DOI: 10.1039/C2OB26637G
Appears in Collections:Environment Institute publications
IPAS publications
Chemistry publications
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