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https://hdl.handle.net/2440/85786
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Type: | Journal article |
Title: | Quantities of Clostridium botulinum organisms and toxin in feces and presence of Clostridium botulinum toxin in the serum of an infant with botulism |
Author: | Paton, J. Lawrence, A. Steven, I. |
Citation: | Journal of Clinical Microbiology, 1983; 17(1):13-15 |
Publisher: | American Society for Microbiology |
Issue Date: | 1983 |
ISSN: | 0095-1137 1098-660X |
Statement of Responsibility: | James C. Paton, Andrew J. Lawrence, and Ian M. Steven |
Abstract: | A 7-week-old boy presented with symptoms and signs characteristic of infant botulism, and the diagnosis was confirmed by the detection of Clostridium botulinum type A organisms and toxin in the feces. The levels of organisms and toxin in the feces were measured throughout the 81-day period in hospital. The maximum levels detected were 2.46 x 10(8) C. botulinum type A colony-forming units and 64,000 mouse 100% lethal doses of type A toxin per g (wet weight) of feces. C. botulinum toxin was also detected in two samples of the patient's serum, collected 3 and 10 days after admission. Improvement in the patient's clinical condition occurred before the levels of organisms and toxin in the feces reached their maxima. A slight improvement may also have occurred while toxin was still present in the serum. |
Keywords: | Feces Humans Clostridium botulinum Botulism Botulinum Toxins Infant Male |
Rights: | © 1983, American Society for Microbiology |
DOI: | 10.1128/jcm.17.1.13-15.1983 |
Published version: | http://jcm.asm.org/content/17/1/13 |
Appears in Collections: | Aurora harvest 2 Molecular and Biomedical Science publications |
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