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PreviewIssue DateTitleAuthor(s)
2009Chaperone-targeting cytotoxin and endoplasmic reticulum stress-inducing drug synergize to kill cancer cellsBacker, J.; Krivoshein, A.; Hamby, C.; Pizzonia, J.; Gilbert, K.; Ray, Y.; Brand, H.; Paton, A.; Paton, J.; Backer, M.
2015Identification of markers that functionally define a quiescent multiple myeloma cell sub-population surviving bortezomib treatmentAdomako, A.; Calvo, V.; Biran, N.; Osman, K.; Chari, A.; Paton, J.; Paton, A.; Moore, K.; Schewe, D.; Aguirre-Ghiso, J.
2013ER stress causes rapid loss of intestinal epithelial stemness through activation of the unfolded protein responseHeijmans, J.; van Lidth de Jeude, J.; Koo, B.; Rosekrans, S.; Wielenga, M.; van de Wetering, M.; Ferrante, M.; Lee, A.; Onderwater, J.; Paton, J.; Paton, A.; Mommaas, A.; Kodach, L.; Hardwick, J.; Hommes, D.; Clevers, H.; Muncan, V.; van den Brink, G.
2010Tissue factor-dependent procoagulant activity of subtilase cytotoxin, a potent AB5 toxin produced by shiga toxigenic Escherichia coliWang, H.; Paton, J.; Thorpe, C.; Bonder, C.; Sun, W.; Paton, A.
2006AB5 subtilase cytotoxin inactivates the endoplasmic reticulum chaperone BiPPaton, A.; Beddoe, T.; Thorpe, C.; Whisstock, J.; Wilce, M.; Rossjohn, J.; Talbot, U.; Paton, J.
2012The Escherichia coli subtilase cytotoxin A subunit specifically cleaves cell-surface GRP78 protein and abolishes COOH-terminal-dependent signalingRay, R.; de Ridder, G.; Eu, J.; Paton, A.; Paton, J.; Pizzo, S.
2011Selective abrogation of BiP/GRP78 blunts activation of NF-κΒ through the ATF6 branch of the UPR: involvement of C/EBPβ and mTOR-dependent dephosphorylation of AktNakajima, S.; Hiramatsu, N.; Hayakawa, K.; Saito, Y.; Kato, H.; Huang, T.; Yao, J.; Paton, A.; Paton, J.; Kitamura, M.
2009Subtilase cytotoxin cleaves newly synthesized BiP and blocks antibody secretion in B lymphocytesHu, C.; Dougan, S.; Winter, S.; Paton, A.; Paton, J.; Ploegh, H.
2012Limitation of individual folding resources in the ER leads to outcomes distinct from the unfolded protein responseEletto, D.; Maganty, A.; Eletto, D.; Dersh, D.; Makarewich, C.; Biswas, C.; Paton, J.; Paton, A.; Doroudgar, S.; Glembotski, C.; Argon, Y.

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