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PreviewIssue DateTitleAuthor(s)
2019OBI-3424, a novel AKR1c3-activated prodrug, exhibits potent efficacy against preclinical models of T-ALLEvans, K.; Duan, J.X.; Pritchard, T.; Jones, C.D.; McDermott, L.; Gu, Z.; Toscan, C.E.; El-Zein, N.; Mayoh, C.; Erickson, S.W.; Guo, Y.; Meng, F.; Jung, D.; Rathi, K.S.; Roberts, K.G.; Mullighan, C.G.; Shia, C.S.; Pearce, T.; Teicher, B.A.; Smith, M.A.; et al.
2019Suppressing fatty acid uptake has therapeutic effects in preclinical models of prostate cancerWatt, M.J.; Clark, A.K.; Selth, L.A.; Haynes, V.R.; Lister, N.; Rebello, R.; Porter, L.H.; Niranjan, B.; Whitby, S.T.; Lo, J.; Huang, C.; Schittenhelm, R.B.; Anderson, K.E.; Furic, L.; Wijayaratne, P.R.; Matzaris, M.; Montgomery, M.K.; Papargiris, M.; Norden, S.; Febbraio, M.; et al.
2015Progesterone receptor modulates ERα action in breast cancerMohammed, H.; Russell, I.; Stark, R.; Rueda, O.; Hickey, T.; Tarulli, G.; Serandour, A.; Birrell, S.; Bruna, A.; Saadi, A.; Menon, S.; Hadfield, J.; Pugh, M.; Raj, G.; Brown, G.; D'Santos, C.; Robinson, J.; Silva, G.; Launchbury, R.; Perou, C.; et al.
2009Lin28 promotes transformation and is associated with advanced human malignanciesViswanathan, S.; Powers, J.; Einhorn, W.; Hoshida, Y.; Ng, T.; Toffanin, S.; O'Sullivan, M.; Lu, J.; Philips, L.; Lockhart, V.; Sha, S.; Tanwar, P.; Mermel, C.; Beroukhim, R.; Azam, M.; Teixeira, J.; Meyerson, M.; Hughes, T.; Llovet, J.; Mullighan, C.; et al.
2012The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinomaPerez-Mancera, P.; Rust, A.; van der Weyden, L.; Kristiansen, G.; Li, A.; Sarver, A.; Silverstein, K.; Grützmann, R.; Aust, D.; Rümmele, P.; Knösel, T.; Herd, C.; Stemple, D.; Kettleborough, R.; Brosnan, J.; Li, A.; Morgan, R.; Knight, S.; Yu, J.; Stegeman, S.; et al.
2012Dual roles of PARP-1 promote cancer growth and progressionSchiewer, M.; Goodwin, J.; Han, S.; Brenner, J.; Augello, M.; Dean, J.; Liu, F.; Planck, J.; Ravindranathan, P.; Chinnaiyan, A.; McCue, P.; Gomella, L.; Raj, G.; Dicker, A.; Brody, J.; Pascal, J.; Centenera, M.; Butler, L.; Tilley, W.; Feng, F.; et al.
2013Combined targeting of JAK2 and Bcl-2/Bcl-xL to cure mutant JAK2-driven malignancies and overcome acquired resistance to JAK2 inhibitorsWaibel, M.; Solomon, V.; Knight, D.; Ralli, R.; Kim, S.; Banks, K.; Vidacs, E.; Virely, C.; Sia, K.; Bracken, L.; Collins-Underwood, R.; Drenberg, C.; Ramsey, L.; Meyer, S.; Takiguchi, M.; Dickins, R.; Levine, R.; Ghysdael, J.; Dawson, M.; Lock, R.; et al.
2017Inhibition of Pol I transcription treats murine and human AML by targeting the leukemia-initiating cell populationHein, N.; Cameron, D.; Hannan, K.; Nguyen, N.; Fong, C.; Sornkom, J.; Wall, M.; Pavy, M.; Cullinane, C.; Diesch, J.; Devlin, J.; George, A.; Sanij, E.; Quin, J.; Poortinga, G.; Verbrugge, I.; Baker, A.; Drygin, D.; Harrison, S.; Rozario, J.; et al.
2017MicroRNA-194 promotes prostate cancer metastasis by inhibiting SOCS2Das, R.; Gregory, P.A.; Fernandes, R.C.; Denis, I.; Wang, Q.; Townley, S.L.; Zhao, S.G.; Hanson, A.; Pickering, M.A.; Armstrong, H.K.; Lokman, N.A.; Ebrahimie, E.; Davicioni, E.; Jenkins, R.B.; Karnes, R.J.; Ross, A.E.; Den, R.B.; Klein, E.A.; Chi, K.N.; Ramshaw, H.S.; et al.

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