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Results 1-10 of 16 (Search time: 0.003 seconds).
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PreviewIssue DateTitleAuthor(s)
1999Identification of a 14-3-3 binding sequence in the common B chain of the granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-3 (IL-3), and IL-5 receptors that is serine-phosphorylated by GM-CSFStomski, F.; Dottore, M.; Winnall, W.; Guthridge, M.; Woodcock, J.; Bagley, C.; Thomas, D.; Andrews, R.; Berndt, M.; Lopez, A.
1997Crucial role of the residue at the F'-G' loop of the human GM-CSF receptor a chain for ligand recognition.Rajotte, D.; Cadieux, C.; Haman, A.; Wilkes, B.; Clark, S.; Hercus, T.; Woodcock, J.; Lopez, A.; Hoang, T.
1996Monoclonal antibody 7G3 recognises the N-terminal domain of the human IL-3 receptor and functions as a specific IL-3 receptor antagonistQiyu, S.; Woodcock, J.; Stomski, F.; Bagley, C.; Goodall, G.; Smith, W.; Vadas, M.; Lopez, A.
2013Targeting acute myeloid leukemia by dual inhibition of PI3K signaling and Cdk9-mediated Mcl-1 transcriptionThomas, D.; Powell, J.; Vergez, F.; Segal, D.; Nguyen, N.; Baker, A.; Teh, T.; Barry, E.; Sarry, J.; Lee, E.; Nero, T.; Jabbour, A.; Giovanna, P.; Green, B.; Manenti, S.; Glaser, S.; Parker, M.; Lopez, A.; Ekert, P.; Lock, R.; et al.
2014Monoclonal antibody targeting of IL-3 receptor α with CSL362 effectively depletes CML progenitor and stem cellsNievergall, E.; Ramshaw, H.; Yong, A.; Biondo, M.; Busfield, S.; Vairo, G.; Lopez, A.; Hughes, T.; White, D.; Hiwase, D.
2015Efficacy of an Fc-modified anti-CD123 antibody (CSL362) combined with chemotherapy in xenograft models of acute myelogenous leukemia in immunodeficient miceLee, E.; Yee, D.; Busfield, S.; McManus, J.; Cummings, N.; Vairo, G.; Wei, A.; Ramshaw, H.; Powell, J.; Lopez, A.; Lewis, I.; McCall, M.; Lock, R.
2001GM-CSF binding to its receptor induces oligomerisation of the common beta-subunitMc Clure, B.; Woodcock, J.; Harrison-Findik, D.; Lopez, A.; D'Andrea, R.
2000The role of disulfide-linked dimerization in interleukin-3 receptor signaling and biological activityLe, F.; Stomski, F.; Woodcock, J.; Lopez, A.; Gonda, T.
2003Threonine 391 phosphorylation of the human prolactin receptor mediates a novel interaction with 14-3-3 proteinsOlayioye, M.; Guthridge, M.; Stomski, F.; Lopez, A.; Visvader, J.; Lindeman, G.
200914-3-3:Shc scaffolds integrate phosphoserine and phosphotyrosine signaling to regulate phosphatidylinositol 3-kinase activation and cell survivalBarry, E.; Felquer, F.; Powell, J.; Biggs, L.; Stomski, F.; Urbani, A.; Ramshaw, H.; Hoffmann, P.; Wilce, M.; Grimbaldeston, M.; Lopez, A.; Guthridge, M.