Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/100241
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Type: Journal article
Title: Ageing is associated with decreases in appetite and energy intake - a meta-analysis in healthy adults
Author: Giezenaar, C.
Chapman, I.
Luscombe-Marsh, N.
Feinle-Bisset, C.
Horowitz, M.
Soenen, S.
Citation: Nutrients, 2016; 8(1):28-1-28-22
Publisher: MDPI AG
Issue Date: 2016
ISSN: 2072-6643
2072-6643
Statement of
Responsibility: 
Caroline Giezenaar, Ian Chapman, Natalie Luscombe-Marsh, Christine Feinle-Bisset, Michael Horowitz, and Stijn Soenen
Abstract: It is not well recognized that in the elderly weight loss is more common than weight gain. The aim of this analysis was to determine the effect of ageing on appetite (hunger/fullness) and energy intake, after overnight fasting and in a postprandial state, by meta-analyses of trials that included at least two age groups (>18 years). We hypothesized that appetite and energy intake would be less in healthy older compared with younger adults. Following a PubMed-database systematic search up to 30 June 2015, 59 studies were included in the random-effects-model meta-analyses. Energy intake was 16%-20% lower in older (n = 3574/~70 years/~71 kg/~25 kg/m²) than younger (n = 4111/~26 years/~69 kg/~23 kg/m²) adults (standardized mean difference: -0.77 (95% confidence interval -0.90 to -0.64)). Hunger was 25% (after overnight fasting; weighted mean difference (WMD): -17 (-22 to -13) mm) to 39% (in a postprandial state; WMD: -14 (-19 to -9) mm) lower, and fullness 37% (after overnight fasting; WMD: 6 mm (95% CI: 1 to 11 mm)) greater in older than younger adults. In conclusion, appetite and energy intake are less in healthy older than younger adults, suggesting that ageing per se affects food intake.
Keywords: Ageing; energy intake; appetite; hunger; fullness; elderly
Rights: © 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
RMID: 0030041412
DOI: 10.3390/nu8010028
Grant ID: http://purl.org/au-research/grants/nhmrc/627002
Appears in Collections:Medicine publications

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