Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/10053
Citations
Scopus Web of Science® Altmetric
?
?
Type: Journal article
Title: Changes in fibrinogen levels in patients undergoing open and laparoscopic Nissen fundoplication
Author: Pike, G.
Bessell, J.
Mathew, G.
Watson, D.
Mitchell, P.
Jamieson, G.
Citation: ANZ Journal of Surgery, 1996; 66(2):94-96
Publisher: BLACKWELL SCIENCE
Issue Date: 1996
ISSN: 0004-8682
1445-2197
Statement of
Responsibility: 
Gregory K. Pike, Justin R. Bessell, George Matthew, David I. Watson, Phillip C. Mitchell and Glyn G. Jamieson
Abstract: <h4>Background</h4>Venous thromboembolic complications may be more common after laparoscopic surgical techniques, possibly due to changes in venous flow and blood coagulability.<h4>Methods</h4>This study assessed fibrinogen, cross-linked fibrin degradation products (D-dimer), prothrombin international normalized ration (INR), activated partial thromboplastic time (APTT) and platelets, during and after both open and laparoscopic Nissen fundoplication to determine whether coagulability is increased by the laparoscopic approach.<h4>Results</h4>Seven patients underwent open and thirteen underwent laparoscopic Nissen fundoplication. Fibrinogen levels following open fundoplication fell from 2.8 +/- 0.3 g/L pre-operatively to 2.0 +/- 0.3 g/L following skin incision, and then increased to 4.1 +/- 0.4 g/L on the first postoperative day. Similar changes in fibrinogen occurred following laparoscopic fundoplication (2.7 +/- 0.2, 2.5 +/ 0.2 and 3.8 +/- 0.4 g/L, respectively). No significant changes in the other coagulation indices were observed.<h4>Conclusions</h4>These results demonstrate hypercoagulability on the first postoperative day, irrespective of the operative technique. No differences between the results following laparoscopic and open fundoplication were demonstrated.
Keywords: Humans
Gastroesophageal Reflux
Fibrinogen
Laparoscopy
Blood Coagulation Tests
Fundoplication
Postoperative Period
Analysis of Variance
Adult
Aged
Middle Aged
Female
Male
Description: Copyright © 2009 Royal Australasian College of Surgeons
Provenance: Published Online: 21 Jan 2008
DOI: 10.1111/j.1445-2197.1996.tb01120.x
Appears in Collections:Aurora harvest
Surgery publications

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.