Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/101152
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Type: Journal article
Title: The biosynthesis and biomimetic synthesis of merochlorins A and B
Author: Pepper, H.
George, J.
Citation: Synlett: accounts and rapid communications in synthetic organic chemistry, 2015; 26(18):2485-2490
Publisher: Georg Thieme Verlag
Issue Date: 2015
ISSN: 0936-5214
1437-2096
Statement of
Responsibility: 
Henry P. Pepper, Jonathan H. George
Abstract: The interplay between biosynthetic studies and biomimetic synthesis is discussed in the context of the merochlorin family of marine natural products. Total syntheses of merochlorin A by our group and merochlorin B by the Trauner group are presented alongside the biosynthetic studies of Moore and co-workers. The common theme is the generation of complex polycyclic ring systems by oxidative dearomatization–cyclization cascade reactions.The interplay between biosynthetic studies and biomimetic synthesis is discussed in the context of the merochlorin family of marine natural products. Total syntheses of merochlorin A by our group and merochlorin B by the Trauner group are presented alongside the biosynthetic studies of Moore and co-workers. The common theme is the generation of complex polycyclic ring systems by oxidative dearomatization–cyclization cascade reactions.
Keywords: Biomimetic synthesis; cascade reactions; natural products; meroterpenoids; oxidative dearomatization
Rights: Copyright status unknown
DOI: 10.1055/s-0035-1560635
Grant ID: http://purl.org/au-research/grants/arc/DE130100689
Appears in Collections:Aurora harvest 3
Chemistry publications

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