Please use this identifier to cite or link to this item:
Scopus Web of ScienceĀ® Altmetric
Type: Journal article
Title: A prospective study of the effect of fundoplication on primary and secondary peristalsis in the esophagus
Author: Tew, S.
Jamieson, G.
Holloway, R.
Ferguson, S.
Tew, P.
Citation: Diseases of the Esophagus, 1997; 10(4):247-252
Publisher: Oxford University Press (OUP)
Issue Date: 1997
ISSN: 1120-8694
Abstract: We studied 13 patients before and after Nissen fundoplication and compared them with 11 healthy volunteers and 12 other patients with dysphagia after fundoplication. Esophageal manometry was performed to assess primary and secondary peristalsis induced by esophageal distention with air and water boluses. In patients with reflux disease, secondary peristalsis was initiated at a median rate of 60% of distending episodes, propagation of the secondary peristaltic wave occurred in 40% and lower oesophageal sphincter relaxation occurred with 70% of secondary peristaltic waves. Fundoplication did not alter the initiation or propagation rate of secondary peristalsis but it decreased the median lower esophageal sphincter relaxation rate to 45% (P < 0.03). Fundoplication was not associated with a change in the amplitude of primary peristaltic waves even in patients complaining of dysphagia. In post-fundoplication patients, successful secondary peristaltic waves had significantly lower (P < 0.005) proximal and distal amplitude than primary peristaltic waves. We conclude that there is no improvement in primary or secondary peristalsis after fundoplication and dysphagia after fundoplication is not due to altered peristalsis.
Keywords: Esophagus
Esophagogastric Junction
Deglutition Disorders
Gastroesophageal Reflux
Esophagitis, Peptic
Analysis of Variance
Case-Control Studies
Prospective Studies
Muscle Relaxation
Middle Aged
DOI: 10.1093/dote/10.4.247
Appears in Collections:Aurora harvest 2
Surgery publications

Files in This Item:
There are no files associated with this item.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.