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Type: Journal article
Title: Concise syntheses of meridianins and meriolins using a catalytic domino amino-palladation reaction
Author: Walker, S.
Czyz, M.
Morris, J.
Citation: Organic Letters, 2014; 16(3):708-711
Publisher: American Chemical Society
Issue Date: 2014
ISSN: 1523-7060
Statement of
Scott R. Walker, Milena L. Czyz, and Jonathan C. Morris
Abstract: A synthesis of natural and synthetic members of the meridianin family of kinase inhibitory natural products has been developed. The sequence utilizes a variation of the Cacchi palladium-catalyzed domino reaction to efficiently construct the heterocyclic framework of the meridianins and meriolins from monocyclic precursors.
Keywords: Syntheses; meridianins; meriolins
Rights: © 2014 American Chemical Society
DOI: 10.1021/ol403390m
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