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https://hdl.handle.net/2440/101443
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Type: | Journal article |
Title: | Concise syntheses of meridianins and meriolins using a catalytic domino amino-palladation reaction |
Author: | Walker, S. Czyz, M. Morris, J. |
Citation: | Organic Letters, 2014; 16(3):708-711 |
Publisher: | American Chemical Society |
Issue Date: | 2014 |
ISSN: | 1523-7060 1523-7052 |
Statement of Responsibility: | Scott R. Walker, Milena L. Czyz, and Jonathan C. Morris |
Abstract: | A synthesis of natural and synthetic members of the meridianin family of kinase inhibitory natural products has been developed. The sequence utilizes a variation of the Cacchi palladium-catalyzed domino reaction to efficiently construct the heterocyclic framework of the meridianins and meriolins from monocyclic precursors. |
Keywords: | Syntheses; meridianins; meriolins |
Rights: | © 2014 American Chemical Society |
DOI: | 10.1021/ol403390m |
Grant ID: | http://purl.org/au-research/grants/arc/DP0706503 |
Appears in Collections: | Aurora harvest 7 Chemistry publications |
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