Please use this identifier to cite or link to this item:
http://hdl.handle.net/2440/101708
Citations | ||
Scopus | Web of Science® | Altmetric |
---|---|---|
?
|
?
|
Type: | Journal article |
Title: | Maternal marijuana use has independent effects on risk for spontaneous preterm birth but not other common late pregnancy complications |
Author: | Leemaqz, S. Dekker, G. McCowan, L. Kenny, L. Myers, J. Simpson, N. Poston, L. Roberts, C. |
Citation: | Reproductive Toxicology, 2016; 62:77-86 |
Publisher: | Elsevier |
Issue Date: | 2016 |
ISSN: | 0890-6238 1873-1708 |
Statement of Responsibility: | Shalem Y. Leemaqz, Gustaaf A. Dekker, Lesley M. McCowan, Louise C. Kenny, Jenny E. Myers, Nigel A.B. Simpson, Lucilla Poston, Claire T. Roberts, On behalf of the SCOPE Consortium |
Abstract: | Widespread legalisation of marijuana raises safety concerns for its use in pregnancy. This study investigated the association of marijuana use prior to and during pregnancy with pregnancy outcomes in a prospective cohort of 5588 nulliparous women from the international SCOPE study. Women were assessed at 15 ± 1 and 20 ± 1 weeks’ gestation. Cases [278 Preeclampsia, 470 gestational hypertension, 633 small-for-gestational-age, 236 spontaneous preterm births (SPTB), 143 gestational diabetes] were compared separately with 4114 non-cases. Although the numbers are small, continued maternal marijuana use at 20 weeks’ gestation was associated with SPTB independent of cigarette smoking status [adj OR 2.28 (95% CI:1.45–3.59)] and socioeconomic index (SEI) [adj OR 2.17 (95% CI:1.41–3.34)]. When adjusted for maternal age, cigarette smoking, alcohol and SEI, continued maternal marijuana use at 20 weeks’ gestation had a greater effect size [adj OR 5.44 (95% CI 2.44–12.11)]. Our data indicate that increasing use of marijuana among young women of reproductive age is a major public health concern. |
Keywords: | Marijuana; smoking; BMI; pregnancy outcome; spontaneous preterm birth |
Rights: | © 2016 The Author(s). Published by Elsevier Inc. This is an open access article under the CC BY-NC-NDlicense (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
RMID: | 0030047208 |
DOI: | 10.1016/j.reprotox.2016.04.021 |
Grant ID: | http://purl.org/au-research/grants/nhmrc/1020749 http://purl.org/au-research/grants/nhmrc/519225 |
Appears in Collections: | Medicine publications |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
hdl_101708.pdf | Published version | 925.21 kB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.