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Type: Journal article
Title: Metal–organic framework coatings as cytoprotective exoskeletons for living cells
Author: Liang, K.
Richardson, J.
Cui, J.
Caruso, F.
Doonan, C.
Falcaro, P.
Citation: Advanced Materials, 2016; 28(36):7910-7914
Publisher: Wiley
Issue Date: 2016
ISSN: 0935-9648
Statement of
Kang Liang, Joseph J. Richardson, Jiwei Cui, Frank Caruso, Christian J. Doonan and Paolo Falcaro
Abstract: The biomimetic mineralization of metal–organic framework (MOF) material on living cells is reported. ZIF-8 can be crystallized on a living cell surface as an exoskeleton that offers physical protection while allowing transport of essential nutrients, thus maintaining cell viability. The MOF shell prevents cell division, leading to an artificially induced pseudo-hibernation state. Cellular functions can be fully restored upon MOF removal.
Keywords: Saccharomyces cerevisiae
Protective Agents
Cell Division
Cell Survival
Biomimetic Materials
Metal-Organic Frameworks
Rights: © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
DOI: 10.1002/adma.201602335
Grant ID:
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Chemistry and Physics publications

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