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https://hdl.handle.net/2440/102823
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dc.contributor.author | O'Donnell, M. | - |
dc.contributor.author | Alkemade, N. | - |
dc.contributor.author | Creamer, M. | - |
dc.contributor.author | McFarlane, A. | - |
dc.contributor.author | Silove, D. | - |
dc.contributor.author | Bryant, R. | - |
dc.contributor.author | Forbes, D. | - |
dc.date.issued | 2016 | - |
dc.identifier.citation | Journal of Clinical Psychiatry, 2016; 77(4):e473-e479 | - |
dc.identifier.issn | 0160-6689 | - |
dc.identifier.issn | 1555-2101 | - |
dc.identifier.uri | http://hdl.handle.net/2440/102823 | - |
dc.description.abstract | Objective: The impact of mental health on disease burden associated with injury represents a major public health issue, yet almost no information is available on the associated long-term mental health outcomes. The primary aim of this study was to assess the psychiatric outcomes 6 years after a severe injury and their subsequent impact on long-term disability. The secondary aim was to investigate the relationship between a mild traumatic brain injury (mTBI) and long-term psychiatric disorder and its impact on disability. Methods: From April 2004 to February 2006, randomly selected injury patients admitted to 4 hospitals across Australia were assessed during hospitalization and at 72 months after trauma (N = 592). Injury characteristics, the presence of an mTBI (ICD-9 criteria), and previous psychiatric history were assessed during hospitalization. Structured clinical interviews for psychiatric disorders (DSM-IV and DSM-5) and a self-report measure of disability (WHODAS II) were administered at 72 months. Results: At 72 months after a severe injury, 28% of patients met criteria for at least 1 psychiatric disorder, with 45% of those presenting with comorbid diagnoses. The most prevalent psychiatric disorder was a major depressive episode (11%) followed by substance use disorder (9%), agoraphobia (9%), posttraumatic stress disorder (6%), and generalized anxiety disorder (6%). The presence of any psychiatric disorder was found to increase the risk for disability (P < .001, odds ratio = 6.04). An mTBI was found to increase the risk for having some anxiety disorders but not to increase disability by itself. Conclusions: The long-term psychiatric consequences of severe injury are substantial and represent a significant contributor to long-term disability. This study points to an important intersection between injury and psychiatric disorder as a leading contributor to disease burden and suggests this growing burden will impose new challenges on health systems. | - |
dc.description.statementofresponsibility | Meaghan L. O, Donnell, Nathan Alkemade, Mark C. Creamer, Alexander C. McFarlane, Derrick Silove, Richard A. Bryant and David Forbes | - |
dc.language.iso | en | - |
dc.publisher | Physicians Postgraduate Press, Inc. | - |
dc.rights | © Copyright 2016 Physicians Postgraduate Press, Inc. | - |
dc.source.uri | http://dx.doi.org/10.4088/jcp.14m09721 | - |
dc.subject | Humans | - |
dc.subject | Brain Concussion | - |
dc.subject | Substance-Related Disorders | - |
dc.subject | Wounds and Injuries | - |
dc.subject | Disability Evaluation | - |
dc.subject | Risk Factors | - |
dc.subject | Retrospective Studies | - |
dc.subject | Follow-Up Studies | - |
dc.subject | Mental Disorders | - |
dc.subject | Anxiety Disorders | - |
dc.subject | Stress Disorders, Post-Traumatic | - |
dc.subject | Depressive Disorder, Major | - |
dc.subject | Adolescent | - |
dc.subject | Adult | - |
dc.subject | Aged | - |
dc.subject | Middle Aged | - |
dc.subject | Female | - |
dc.subject | Male | - |
dc.subject | Young Adult | - |
dc.title | The long-term psychiatric sequelae of severe injury: a 6-year follow-up study | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.4088/JCP.14m09721 | - |
dc.relation.grant | http://purl.org/au-research/grants/nhmrc/568970 | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | McFarlane, A. [0000-0002-3829-9509] | - |
Appears in Collections: | Aurora harvest 3 Medicine publications |
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