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Type: Journal article
Title: Sustained improvements in dyspnea and pulmonary function 3 to 5 years after lung volume reduction surgery
Author: Appleton, S.
Adams, R.
Porter, S.
Peacock, M.
Ruffin, R.
Citation: Chest, 2003; 123(6):1838-1846
Publisher: Amer Coll Chest Physicians
Issue Date: 2003
ISSN: 0012-3692
Statement of
Appleton, Sarah, Adams, Robert, Porter, Samuel, Peacock, Morris and Ruffin, Richard
Abstract: Objectives: To determine long-term survival rates of patients who underwent lung volume reduction surgery (LVRS) for emphysema and the factors associated with longer survival, and to evaluate levels of perceived dyspnea and health-related quality of life (HRQL) after a follow-up period of 3 to 5.5 years. Design: Retrospective observational study. Setting: Academic medical center Methods: Telephone and postal surveys were used to obtain patient dyspnea scores and HRQL scores. Hospital databases and state registries were searched to determine patient survival and pulmonary function. Results: Of 54 patients undergoing LVRS, 29 patients (18 men and 11 women) were available for follow-up, which ranged from 36 to 66 months (mean ± SE, 51 ± 1.5 months). There was significant sustained improvement in modified Medical Research Council scores compared to pre-LVRS: 2.19 ± 0.19 vs 2.88 ± 0.14 (p = 0.0000). Eleven of 22 patients demonstrated an increase in all three Mahler baseline dyspnea index grades of at least one level. Baseline body mass index (BMI) and post-LVRS length of stay (LOS) were significantly associated with survival: survivor vs deceased baseline BMI, 24.2 ± 0.6 vs 21.4 ± 0.5 (p = 0.002), and post-LVRS LOS, 15.4 ± 1.7 days vs 28.7 ± 5.3 days (p = 0.015). Compared to pre-LVRS, 20 patients with mean follow-up time of 45 months demonstrated significant sustained improvements in FEV[sub 1] percentage of predicted (31.4 ± 2.1% vs 39.8 ± 3.5%, p = 0.038), total lung capacity percentage of predicted (136 ± 4% vs 122 ± 3%, p = 0.0004), and residual volume percentage of predicted (237 ± 14% vs 172 ± 11%, p = 0.0001). Patient HRQL measured using the Dartmouth Primary Care Co-operative Quality of Life questionnaire was more favorable than that reported in aged-care settings. Caregiver burden scale scores indicate caring for a recipient of LVRS carries similar burden to...
Keywords: Dyspnea; Lungs -- Surgery
Description: © 2003 EBSCO Industries
RMID: 0020030145
DOI: 10.1378/chest.123.6.1838
Appears in Collections:Surgery publications

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