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Type: Journal article
Title: A mesoporous organosilica nano-bowl with high DNA loading capacity - a potential gene delivery carrier
Author: Xiong, L.
Qiao, S.
Citation: Nanoscale, 2016; 8(40):17446-17450
Publisher: Royal Society of Chemistry
Issue Date: 2016
ISSN: 2040-3364
Statement of
Lin Xiong and Shi-Zhang Qiao
Abstract: Mesoporous organosilica nanoparticles with a novel bowl-like morphology were synthesized. These nano-bowls possess uniform particle sizes around 180 nm and open cavities around 140 nm, which lead to higher loading capability for plasmid DNA than traditional silica-based nanoparticles. In vitro DNA transfection using these nano-bowls is demonstrated.
Keywords: Silicon Dioxide; DNA; Gene Transfer Techniques; Genetic Vectors; Porosity; Nanoparticles
Rights: This journal is © The Royal Society of Chemistry 2016
RMID: 0030057370
DOI: 10.1039/c6nr06777h
Appears in Collections:Chemical Engineering publications

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