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https://hdl.handle.net/2440/105614
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dc.contributor.author | Bader, C. | - |
dc.contributor.author | Sorvina, A. | - |
dc.contributor.author | Simpson, P. | - |
dc.contributor.author | Wright, P. | - |
dc.contributor.author | Stagni, S. | - |
dc.contributor.author | Plush, S. | - |
dc.contributor.author | Massi, M. | - |
dc.contributor.author | Brooks, D. | - |
dc.date.issued | 2016 | - |
dc.identifier.citation | FEBS Letters, 2016; 590(18):3051-3060 | - |
dc.identifier.issn | 0014-5793 | - |
dc.identifier.issn | 1873-3468 | - |
dc.identifier.uri | http://hdl.handle.net/2440/105614 | - |
dc.description.abstract | Live cell imaging can provide important information on cellular dynamics; however, the full utilisation of this technology has been hampered by the limitations of imaging reagents. Metal-based complexes have the potential to overcome many of the issues common to many current imaging agents. The rhenium (I)-based complex fac-[Re(CO)3 (1,10-phenanthroline)(4-pyridyltetrazolate)], herein referred to as ReZolve-ER(™) , shows promise as a live cell imaging agent with rapid cell uptake, low cytotoxicity, resistance to photobleaching and compatibility with multicolour imaging. ReZolve-ER(™) localised to the nuclear membrane/endoplasmic reticulum (ER) and allowed the detection of exocytotic events at the plasma membrane. Thus, we present a new imaging agent for monitoring live cell events in real time, which is ideal for imaging either short- or long-time courses. | - |
dc.description.statementofresponsibility | Christie A. Bader, Alexandra Sorvina, Peter V. Simpson, Phillip J. Wright, Stefano Stagni, Sally E. Plush, Massimiliano Massi and Douglas A. Brooks | - |
dc.language.iso | en | - |
dc.publisher | Wiley-Blacwell | - |
dc.rights | © 2016 Federation of European Biochemical Societies | - |
dc.source.uri | http://dx.doi.org/10.1002/1873-3468.12365 | - |
dc.subject | Endoplasmic reticulum; live cell imaging; rhenium | - |
dc.title | Imaging nuclear, endoplasmic reticulum and plasma membrane events in real time | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1002/1873-3468.12365 | - |
dc.relation.grant | http://purl.org/au-research/grants/arc/FT130100033 | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Brooks, D. [0000-0001-9098-3626] | - |
Appears in Collections: | Aurora harvest 3 Biochemistry publications |
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