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https://hdl.handle.net/2440/105752
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dc.contributor.author | Edney, L. | - |
dc.contributor.author | Burns, N. | - |
dc.contributor.author | Danthiir, V. | - |
dc.date.issued | 2015 | - |
dc.identifier.citation | The British Journal of Nutrition: an international journal of nutritional science, 2015; 114(8):1321-1328 | - |
dc.identifier.issn | 0007-1145 | - |
dc.identifier.issn | 1475-2662 | - |
dc.identifier.uri | http://hdl.handle.net/2440/105752 | - |
dc.description.abstract | Vitamin B₁₂, folate and homocysteine have long been implicated in mental illness, and growing evidence suggests that they may play a role in positive mental health. Elucidation of these relationships is confounded due to the dependence of homocysteine on available levels of vitamin B₁₂ and folate. Cross-sectional and longitudinal relationships between vitamin B₁₂, folate, homocysteine and subjective well-being were assessed in a sample of 391 older, community-living adults without clinically diagnosed depression. Levels of vitamin B₁₂, but not folate, influenced homocysteine levels 18 months later. Vitamin B₁₂, folate and their interaction significantly predicted levels of positive affect (PA) 18 months later, but had no impact on the levels of negative affect or life satisfaction. Cross-sectional relationships between homocysteine and PA were completely attenuated in the longitudinal analyses, suggesting that the cross-sectional relationship is driven by the dependence of homocysteine on vitamin B₁₂ and folate. This is the first study to offer some evidence of a causal link between levels of folate and vitamin B₁₂ on PA in a large, non-clinical population. | - |
dc.description.statementofresponsibility | Laura C. Edney, Nicholas R. Burns and Vanessa Danthiir | - |
dc.language.iso | en | - |
dc.publisher | Cambridge University Press | - |
dc.rights | © The Authors 2015 | - |
dc.source.uri | http://dx.doi.org/10.1017/s0007114515002949 | - |
dc.subject | Folate; homocysteine; positive affect; subjective well-being; vitamin B12 | - |
dc.title | Subjective well-being in older adults: folate and vitamin B₁₂ independently predict positive affect | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1017/S0007114515002949 | - |
dc.relation.grant | http://purl.org/au-research/grants/nhmrc/578800 | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Edney, L. [0000-0002-2447-4118] | - |
dc.identifier.orcid | Burns, N. [0000-0003-3456-6734] | - |
Appears in Collections: | Aurora harvest 8 Psychology publications |
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