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|Title:||Impact of a history of maternal depression and anxiety on asthma control during pregnancy|
|Citation:||Journal of Asthma, 2017; 54(7):706-713|
|Publisher:||Taylor & Francis|
|Luke E. Grzeskowiak, Brian Smith, Anil Roy, K. Oliver Schubert, Bernhard T. Baune, Gustaaf A. Dekker, and Vicki L. Clifton|
|Abstract:||Objective: To determine the impact of self-reported maternal depression/anxiety on asthma control during pregnancy. Method: Pregnant women with a doctor diagnosis of asthma (n = 189) were prospectively recruited at their antenatal booking visit and the presence of maternal depression and anxiety was identified using self-report and routine questionnaire assessments. Data on exacerbations and asthma control were collected during gestation. Asthma control was assessed using the Juniper asthma control questionnaire and women were classified as having recurrent uncontrolled asthma if their ACQ score was > 1.5 during two or more consecutive study visits. Exacerbations were defined as events that lead to increased treatment requirements, doctor or hospital visits. Results: There were 85 women with self-reported depression/anxiety and 104 women without self-reported depression/anxiety. The presence of depression/anxiety was associated with an increased likelihood (adjusted HR 1.67: 95% CI 1.03-2.72), and incidence (adjusted IRR 1.71: 95% CI 1.13-2.58) of uncontrolled asthma during pregnancy, as well an increased risk of recurrent uncontrolled asthma during 2 or more study visits (adjusted RR 1.98: 95% CI 1.00-3.91). No impact of depression/anxiety was observed with respect to the likelihood (adjusted HR 0.70: 95% CI 0.35-1.41) or incidence of exacerbations during pregnancy (adjusted IRR 0.66: 95% CI 0.35-1.26). Conclusions: This study provides evidence that the presence of maternal depression/anxiety is associated with an increased likelihood and incidence of uncontrolled asthma during pregnancy. Given the high prevalence of comorbid depression/anxiety among asthmatics, further research investigating such associations is urgently required.|
|Keywords:||Anxiety; asthma; asthma control; depression; mental health; pregnancy|
|Rights:||© 2015 Taylor & Francis Group, LLC|
|Appears in Collections:||Paediatrics publications|
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