Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/109328
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Type: Journal article
Title: Sperm donation perinatal outcomes in an Australian population cohort
Author: Adams, D.
Fernandez, R.
Moore, V.
Willson, K.
Rumbold, A.
de Lacey, S.
Scheil, W.
Davies, M.
Citation: The Journal of Obstetrics and Gynaecology Research, 2017; 43(12):1830-1839
Publisher: Wiley-Blackwell
Issue Date: 2017
ISSN: 1341-8076
1447-0756
Abstract: Aim: To compare perinatal outcomes for neonates conceived with donated sperm with those for neonates conceived spontaneously in an Australian population cohort. Methods: Perinatal outcomes for all births in South Australia for the period January 1986–December 2002 were linked with assisted reproductive treatment records to determine those conceived from donated sperm. Birth outcome measures were analyzed using Student’s t-test and logistic regression using generalized estimating equations to determine statistical significance. Results: Donor sperm neonates were not significantly different fromtheir spontaneously conceived counterparts in terms ofmean birthweight, low birthweight, pretermdelivery, small for gestational age, or large for gestational age. They were, however, significantly more likely to be born at lower mean gestational age (P = 0.012), and to have preterm delivery with low birthweight (P = 0.008), when controlling for maternal age, parity, ethnicity, socioeconomic quartile and baby’s sex. These associations were not apparent when singletons and twins were considered separately. Conclusion: There was some evidence of compromised perinatal outcomes for donor sperm neonates compared with their spontaneously conceived counterparts, which appeared to be partly attributable to multiplicity.
Keywords: donor conception; infant; insemination artificial; population; spermatozoa
RMID: 0030074277
DOI: 10.1111/jog.13449
Grant ID: http://purl.org/au-research/grants/nhmrc/349475
http://purl.org/au-research/grants/nhmrc/349548
http://purl.org/au-research/grants/nhmrc/453556
http://purl.org/au-research/grants/nhmrc/465455
http://purl.org/au-research/grants/arc/FT100101018
Published version: https://www.ncbi.nlm.nih.gov/pubmed/28816393
Appears in Collections:Public Health publications

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