Please use this identifier to cite or link to this item:
|Scopus||Web of Science®||Altmetric|
|Title:||Comparing oncological outcomes of laparoscopic versus open surgery for colon cancer: Analysis of a large prospective clinical database|
|Citation:||Journal of Surgical Oncology, 2015; 111(7):891-898|
|T. Sammour, Ian T. Jones, P. Gibbs, R. Chandra, Malcolm C. Steel, Susan M. Shedda, M. Croxford, I. Faragher, Ian P. Hayes and Ian A. Hastie|
|Abstract:||BACKGROUND: Oncological outcomes of laparoscopic colon cancer surgery have been shown to be equivalent to those of open surgery, but only in the setting of randomized controlled trials on highly selected patients. The aim of this study is to investigate whether this finding is generalizable to real world practice. METHODS: Analysis of prospectively collected data from the BioGrid Australia database was undertaken. Overall and cancer specific survival rates were compared with cox regression analysis controlling for the confounders of age, sex, BMI, ASA score, hospital site, year surgery performed, procedure, tumor stage, and adjuvant chemotherapy. RESULTS: Between 2003 and 2009, 1,106 patients underwent elective colon cancer resection. There were differences between the laparoscopic and open cohorts in BMI, procedure, post-operative complication rate, and tumor stage. When baseline confounders were accounted for using cox regression analysis, there was no difference in 5 year overall survival (chi(2) test 1.302, P = 0.254), or cancer specific survival (chi(2) test 0.028, P = 0.866). CONCLUSION: This large prospective clinical study validates previous trial results, and confirms that there is no difference in oncological outcome between laparoscopic and open surgery for colon cancer.|
|Keywords:||Aged Australia Colectomy/*mortality Colonic Neoplasms/mortality/pathology/*surgery Female Follow-Up Studies Humans Laparoscopy/*mortality Length of Stay Male Neoplasm Staging Postoperative Complications/*mortality Prognosis Prospective Studies Survival Rate colon cancer laparoscopy oncology rectal cancer survival|
|Rights:||© 2015 Wiley Periodicals, Inc.|
|Appears in Collections:||Aurora harvest 3|
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.