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Type: Journal article
Title: Automatic localization of the left ventricular blood pool centroid in short axis cardiac cine MR images
Author: Tan, L.
Liew, Y.
Lim, E.
Abdul Aziz, Y.
Chee, K.
McLaughlin, R.
Citation: Medical and Biological Engineering and Computing, 2018; 56(6):1053-1062
Publisher: Springer
Issue Date: 2018
ISSN: 0140-0118
Statement of
Li Kuo Tan, Yih Miin Liew, Einly Lim, Yang Faridah Abdul Aziz, Kok Han Chee and Robert A McLaughlin
Abstract: In this paper, we develop and validate an open source, fully automatic algorithm to localize the left ventricular (LV) blood pool centroid in short axis cardiac cine MR images, enabling follow-on automated LV segmentation algorithms. The algorithm comprises four steps: (i) quantify motion to determine an initial region of interest surrounding the heart, (ii) identify potential 2D objects of interest using an intensity-based segmentation, (iii) assess contraction/expansion, circularity, and proximity to lung tissue to score all objects of interest in terms of their likelihood of constituting part of the LV, and (iv) aggregate the objects into connected groups and construct the final LV blood pool volume and centroid. This algorithm was tested against 1140 datasets from the Kaggle Second Annual Data Science Bowl, as well as 45 datasets from the STACOM 2009 Cardiac MR Left Ventricle Segmentation Challenge. Correct LV localization was confirmed in 97.3% of the datasets. The mean absolute error between the gold standard and localization centroids was 2.8 to 4.7 mm, or 12 to 22% of the average endocardial radius.
Keywords: Cardiovascular MRI; automatic localization; segmentation; left ventricle; cine MRI
Rights: © International Federation for Medical and Biological Engineering 2017
RMID: 0030077805
DOI: 10.1007/s11517-017-1750-7
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Medicine publications

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