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Type: Theses
Title: Pentose phosphate pathway metabolism and glutathione in the host mucosal response to Helicobacter pylori infection
Author: Matthews, Geoffrey Mark
Issue Date: 2000
School/Discipline: Dept. of Physiology
Abstract: Recent studies have suggested a major role of reactive oxygen species (ROS) in the mediation of Helicobacter pylori associated disease. Hence, the severity of mucosal damage during such infection is likely to be dependent on the ability of mucosal cells to counteract the ROS load. The aim of this thesis was to investigate both the activity of the oxidative pentose pathway of glucose metabolism, and glutathione levels in the host response to Helicobacter pylori infection in both a mouse model and in adult symptomatic patrents.
Dissertation Note: Thesis (M.Sc.) -- University of Adelaide, Dept. of Physiology, 2002.
Provenance: This electronic version is made publicly available by the University of Adelaide in accordance with its open access policy for student theses. Copyright in this thesis remains with the author. This thesis may incorporate third party material which has been used by the author pursuant to Fair Dealing exceptions. If you are the owner of any included third party copyright material you wish to be removed from this electronic version, please complete the take down form located at:
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