1. Adelaide Research & Scholarship
  2. Schools and Disciplines
  3. School of Medicine
  4. Medicine
  5. Medicine publications
Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/111290
Citations
Scopus Web of Science® Altmetric
?
?
Full metadata record
DC FieldValueLanguage
dc.contributor.authorSymonds, E.-
dc.contributor.authorFenech, M.-
dc.date.issued2012-
dc.identifier.citationBiological Procedures Online, 2012; 14(1):1-3-
dc.identifier.issn1480-9222-
dc.identifier.issn1480-9222-
dc.identifier.urihttp://hdl.handle.net/2440/111290-
dc.description.abstractThe APC(min/+) mouse is commonly used in cancer research and is just one of many genetically altered models that is currently being developed. With high numbers of breeding programs, it is important to have a simple method that can be used to genotype the mice non-invasively. Here we report a reproducible method for genotyping mice with DNA extracted from fecal samples. Comparison of fecal results with those obtained from intestinal tissue DNA and clinical outcome (presence/absence of tumors) showed this technique to have 100% accuracy. This non-invasive method of genotyping may be applied to other transgenic mouse models.-
dc.description.statementofresponsibilityErin L Symonds and Michael Fenech-
dc.language.isoen-
dc.publisherBioMed Central-
dc.rights© 2012 Symonds and Fenech; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.-
dc.source.urihttp://dx.doi.org/10.1186/1480-9222-14-1-
dc.subjectAPC(min/+); feces; genotyping; cancer; non-invasive-
dc.titleA method for non-invasive genotyping of APC(min+) mice using fecal samples-
dc.typeJournal article-
dc.identifier.doi10.1186/1480-9222-14-1-
dc.relation.granthttp://purl.org/au-research/grants/nhmrc/357702-
pubs.publication-statusPublished-
dc.identifier.orcidFenech, M. [0000-0002-8466-0991]-
Appears in Collections:Aurora harvest 8
Medicine publications

Files in This Item:
File Description SizeFormat 
hdl_111290.pdfPublished version364.56 kBAdobe PDFView/Open
Show simple item record


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.