Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/111782
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dc.contributor.author | Gow, M. | - |
dc.contributor.author | Baur, L. | - |
dc.contributor.author | Ho, M. | - |
dc.contributor.author | Chisholm, K. | - |
dc.contributor.author | Noakes, M. | - |
dc.contributor.author | Cowell, C. | - |
dc.contributor.author | Garnett, S. | - |
dc.date.issued | 2016 | - |
dc.identifier.citation | International Journal of Behavioral Nutrition and Physical Activity, 2016; 13(1):43-1-43-11 | - |
dc.identifier.issn | 1479-5868 | - |
dc.identifier.issn | 1479-5868 | - |
dc.identifier.uri | http://hdl.handle.net/2440/111782 | - |
dc.description.abstract | Background: Lifestyle interventions in adolescents with obesity can result in weight loss following active intervention but individual responses vary widely. This study aimed to identify predictors of weight loss at 12- and 24-months in adolescents with obesity and clinical features of insulin resistance. Methods: Adolescents (n = 111, 66 girls, aged 10–17 years) were participants in a randomised controlled trial, the RESIST study, examining the effects of two diets differing in macronutrient content on insulin sensitivity. Eighty-five completed the 12-month program and 24-month follow-up data were available for 42 adolescents. Change in weight was determined by BMI expressed as a percentage of the 95th percentile (BMI95). The study physician collected socioeconomic data at baseline. Physical activity and screen time, and psychological dimensions of eating behavior were self-reported using the validated CLASS and EPI-C questionnaires, respectively. Stepwise multiple regressions were conducted to identify models that best predicted change in BMI95 at 12- and 24-months. Results: Mean BMI95 was reduced at 12-months compared with baseline (mean difference [MD] ± SE: -6.9 ± 1.0, P < 0.001) but adolescents had significant re-gain from 12- to 24-months (MD ± SE: 3.7 ± 1.5, P = 0.017). Participants who achieved greater 12-month weight loss had: greater 3-month weight loss, a father with a higher education, lower baseline external eating and parental pressure to eat scores and two parents living at home. Participants who achieved greater 24-month weight loss had: greater 12-month weight loss and a lower baseline emotional eating score. Conclusions: Early weight loss is consistently identified as a strong predictor of long-term weight loss. This could be because early weight loss identifies those more motivated and engaged individuals. Patients who have baseline factors predictive of long-term weight loss failure may benefit from additional support during the intervention. Additionally, if a patient does not achieve early weight loss, further support or transition to an alternate intervention where they may have increased success may be considered. | - |
dc.description.statementofresponsibility | Megan L. Gow, Louise A. Baur, Mandy Ho, Kerryn Chisholm, Manny Noakes, Chris T. Cowell and Sarah P. Garnett | - |
dc.language.iso | en | - |
dc.publisher | BioMed Central | - |
dc.rights | © Gow et al. 2016. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. | - |
dc.source.uri | http://dx.doi.org/10.1186/s12966-016-0367-9 | - |
dc.subject | Pediatric; obesityInsulin resistance; predictors; eating behaviors; socioeconomic; weight loss; RESIST | - |
dc.title | Can early weight loss, eating behaviors and socioeconomic factors predict successful weight loss at 12- and 24-months in adolescents with obesity and insulin resistance participating in a randomised controlled trial? | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1186/s12966-016-0367-9 | - |
dc.relation.grant | http://purl.org/au-research/grants/nhmrc/457225 | - |
pubs.publication-status | Published | - |
Appears in Collections: | Aurora harvest 8 Medicine publications |
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hdl_111782.pdf | Published version | 879.3 kB | Adobe PDF | View/Open |
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