Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/111946
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Type: Journal article
Title: Effect of low perceived social support on health outcomes in young patients with acute myocardial infarction: results from the VIRGO (variation in recovery: role of gender on outcomes of young AMI patients) study
Author: Bucholz, E.
Strait, K.
Dreyer, R.
Geda, M.
Spatz, E.
Bueno, H.
Lichtman, J.
D'Onofrio, G.
Spertus, J.
Krumholz, H.
Citation: Journal of the American Heart Association, 2014; 3(5):e001252-1-e001252-11
Publisher: Wiley-Blackwell
Issue Date: 2014
ISSN: 2047-9980
2047-9980
Statement of
Responsibility: 
Emily M. Bucholz, Kelly M. Strait, Rachel P. Dreyer, Mary Geda, Erica S. Spatz, Hector Bueno, Judith H. Lichtman, Gail D'Onofrio, John A. Spertus, Harlan M. Krumholz
Abstract: Background: Social support is an important predictor of health outcomes after acute myocardial infarction (AMI), but social support varies by sex and age. Differences in social support could account for sex differences in outcomes of young patients with AMI. Methods and Results: Data from the Variation in Recovery: Role of Gender on Outcomes of Young AMI Patients (VIRGO) study, an observational study of AMI patients aged ≤55 years in the United States and Spain, were used for this study. Patients were categorized as having low versus moderate/high perceived social support using the ENRICHD Social Support Inventory. Outcomes included health status (Short Form-12 physical and mental component scores), depressive symptoms (Patient Health Questionnaire), and angina-related quality of life (Seattle Angina Questionnaire) evaluated at baseline and 12 months. Among 3432 patients, 21.2% were classified as having low social support. Men and women had comparable levels of social support at baseline. On average, patients with low social support reported lower functional status and quality of life and more depressive symptoms at baseline and 12 months post-AMI. After multivariable adjustment, including baseline health status, low social support was associated with lower mental functioning, lower quality of life, and more depressive symptoms at 12 months (all P<0.001). The relationship between low social support and worse physical functioning was nonsignificant after adjustment (P=0.6). No interactions were observed between social support, sex, or country. Conclusion: Lower social support is associated with worse health status and more depressive symptoms 12 months after AMI in both young men and women. Sex did not modify the effect of social support.
Keywords: Myocardial Infarction
sex
prognosis
Rights: © 2014 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
DOI: 10.1161/JAHA.114.001252
Grant ID: 1ULRR033179
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