Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/112112
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Type: Journal article
Title: Miniaturized single-fiber-based needle probe for combined imaging and sensing in deep tissue
Author: Li, J.
Schartner, E.
Musolino, S.
Quirk, B.
Kirk, R.
Ebendorff-Heidepriem, H.
McLaughlin, R.
Citation: Optics Letters, 2018; 43(8):1682-1685
Publisher: Optical Society of America
Issue Date: 2018
ISSN: 0146-9592
1539-4794
Statement of
Responsibility: 
Jiawen Li, Erik Schartner, Stefan Musolino, Bryden C. Quirk, Rodney W. Kirk, Heike Ebendorff-Heidepriem and Robert A. McLaughlin
Abstract: The ability to visualize structure whilst simultaneously measuring chemical or physical properties of a biological tissue has the potential to improve our understanding of complex biological processes. We report the first miniaturized single-fiber-based imaging+sensing probe capable of simultaneous optical coherence tomography (OCT) imaging and temperature sensing. An OCT lens is fabricated at the distal end of a double clad fiber, including a thin layer of rare-earth doped tellurite glass to enable temperature measurements. The high refractive index of the tellurite glass enables a common-path interferometer configuration for OCT, allowing easy exchange of probes for biomedical applications. The simultaneous imaging+sensing capability is demonstrated on rat brains.
Keywords: Brain; Animals; Rats; Diagnostic Imaging; Tomography, Optical Coherence; Body Temperature; Equipment Design; Fiber Optic Technology; Optical Fibers
Rights: © 2018 Optical Society of America
RMID: 0030085969
DOI: 10.1364/OL.43.001682
Grant ID: http://purl.org/au-research/grants/arc/CE140100003
http://purl.org/au-research/grants/arc/DP150104660
http://purl.org/au-research/grants/arc/LP110200736
Published version: https://doi.org/10.1364/OL.43.001682
Appears in Collections:IPAS publications
Medicine publications

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