Please use this identifier to cite or link to this item:
|Scopus||Web of Science®||Altmetric|
|Title:||Changes in neural connectivity and memory following a yoga intervention for older adults: a pilot study|
Van Dyk, K.
|Citation:||Journal of Alzheimer's Disease, 2016; 52(2):673-684|
|Harris A. Eyre, Bianca Acevedo, Hongyu Yang, Prabha Siddarth, Kathleen Van Dyk, Linda Ercoli, Amber M. Leaver, Natalie St. Cyr, Katherine Narr, Bernhard T. Baune, Dharma S. Khalsa and Helen Lavretsky|
|Abstract:||Background: No study has explored the effect of yoga on cognitive decline and resting-state functional connectivity. Objectives: This study explored the relationship between performance on memory tests and resting-state functional connectivity before and after a yoga intervention versus active control for subjects with mild cognitive impairment (MCI). Methods: Participants ( ≥ 55 y) with MCI were randomized to receive a yoga intervention or active “gold-standard” control (i.e., memory enhancement training (MET)) for 12 weeks. Resting-state functional magnetic resonance imaging was used to map correlations between brain networks and memory performance changes over time. Default mode networks (DMN), language and superior parietal networks were chosen as networks of interest to analyze the association with changes in verbal and visuospatial memory performance. Results: Fourteen yoga and 11 MET participants completed the study. The yoga group demonstrated a statistically significant improvement in depression and visuospatial memory. We observed improved verbal memory performance correlated with increased connectivity between the DMN and frontal medial cortex, pregenual anterior cingulate cortex, right middle frontal cortex, posterior cingulate cortex, and left lateral occipital cortex. Improved verbal memory performance positively correlated with increased connectivity between the language processing network and the left inferior frontal gyrus. Improved visuospatial memory performance correlated inversely with connectivity between the superior parietal network and the medial parietal cortex. Conclusion:Yoga may be as effective as MET in improving functional connectivity in relation to verbal memory performance. These findings should be confirmed in larger prospective studies.|
|Keywords:||Brain; Neural Pathways; Humans; Magnetic Resonance Imaging; Yoga; Pilot Projects; Learning; Memory; Neuropsychological Tests; Functional Neuroimaging; Cognitive Dysfunction|
|Rights:||© 2016 – IOS Press and the authors. All rights reserved This article is published online with Open Access and distributed under the terms of the Creative Commons Attribution Non-Commercial License.|
|Appears in Collections:||Medicine publications|
Files in This Item:
|hdl_112751.pdf||Published Version||2.85 MB||Adobe PDF||View/Open|
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.