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Type: Journal article
Title: Excess stroke incidence in young Aboriginal people in South Australia: pooled results from two population-based studies
Author: Balabanski, A.
Newbury, J.
Leyden, J.
Arima, H.
Anderson, C.
Castle, S.
Cranefield, J.
Paterson, T.
Thrift, A.
Katzenellenbogen, J.
Brown, A.
Kleinig, T.
Citation: International Journal of Stroke, 2018; 13(8):811-814
Publisher: SAGE Publications
Issue Date: 2018
ISSN: 1747-4930
Statement of
Anna H Balabanski, Jonathan Newbury, James M Leyden, Hisatomi Arima, Craig S Anderson, Sally Castle, Jennifer Cranefield, Tracey Paterson, Amanda G Thrift, Judith Katzenellenbogen, Alex Brown, and Timothy J Kleinig
Abstract: Background: Retrospective data indicate increased stroke incidence in Aboriginal/Torres Strait Islander (Indigenous) Australians, possibly with poorer outcomes. We present the first prospective population-based stroke incidence study in Indigenous Australians. Methods: We pooled data from ASCEND and SEARCH, two prospective "ideal" South Australian stroke incidence studies, ASCEND conducted in urban Northwestern Adelaide (2009-2010) and SEARCH in five South Australian rural centers (2009-2011). We calculated age-standardized incidence for Aboriginal and non-Aboriginal people. Results: The study population comprised 261,403 inhabitants. Among 432 first-ever strokes, 13 were in Aboriginal people (median age 51 vs. 78 years for non-Aboriginal people, p < 0.001). Age-standardized stroke incidence per 100,000 in Aboriginal patients (116, 95% CI: 95-137) was nearly two-fold that of non-Aboriginal patients (67, 95% CI: 51-84). Age-stratified excess incidence in Aboriginal people was restricted to those aged < 55 years (incidence rate ratio (IRR) 3.5, 95% CI: 2-7), particularly for intracerebral hemorrhage (IRR: 16, 95% CI: 4-61). Conclusion: The excess stroke incidence in Aboriginal South Australians appears substantial, especially in those aged <55 years. Further work is required to delineate and address disparities.
Keywords: Stroke; epidemiology; Aboriginal; ischemic stroke; hemorrhagic stroke
Rights: © 2018 World Stroke Organization Reprints and permissions:
RMID: 0030087484
DOI: 10.1177/1747493018778113
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