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https://hdl.handle.net/2440/114316
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Type: | Journal article |
Title: | Excess stroke incidence in young Aboriginal people in South Australia: pooled results from two population-based studies |
Author: | Balabanski, A. Newbury, J. Leyden, J. Arima, H. Anderson, C. Castle, S. Cranefield, J. Paterson, T. Thrift, A. Katzenellenbogen, J. Brown, A. Kleinig, T. |
Citation: | International Journal of Stroke, 2018; 13(8):811-814 |
Publisher: | SAGE Publications |
Issue Date: | 2018 |
ISSN: | 1747-4930 1747-4949 |
Statement of Responsibility: | Anna H Balabanski, Jonathan Newbury, James M Leyden, Hisatomi Arima, Craig S Anderson, Sally Castle, Jennifer Cranefield, Tracey Paterson, Amanda G Thrift, Judith Katzenellenbogen, Alex Brown, and Timothy J Kleinig |
Abstract: | Background: Retrospective data indicate increased stroke incidence in Aboriginal/Torres Strait Islander (Indigenous) Australians, possibly with poorer outcomes. We present the first prospective population-based stroke incidence study in Indigenous Australians. Methods: We pooled data from ASCEND and SEARCH, two prospective "ideal" South Australian stroke incidence studies, ASCEND conducted in urban Northwestern Adelaide (2009-2010) and SEARCH in five South Australian rural centers (2009-2011). We calculated age-standardized incidence for Aboriginal and non-Aboriginal people. Results: The study population comprised 261,403 inhabitants. Among 432 first-ever strokes, 13 were in Aboriginal people (median age 51 vs. 78 years for non-Aboriginal people, p < 0.001). Age-standardized stroke incidence per 100,000 in Aboriginal patients (116, 95% CI: 95-137) was nearly two-fold that of non-Aboriginal patients (67, 95% CI: 51-84). Age-stratified excess incidence in Aboriginal people was restricted to those aged < 55 years (incidence rate ratio (IRR) 3.5, 95% CI: 2-7), particularly for intracerebral hemorrhage (IRR: 16, 95% CI: 4-61). Conclusion: The excess stroke incidence in Aboriginal South Australians appears substantial, especially in those aged <55 years. Further work is required to delineate and address disparities. |
Keywords: | Stroke; epidemiology; Aboriginal; ischemic stroke; hemorrhagic stroke |
Rights: | © 2018 World Stroke Organization Reprints and permissions: sagepub.co.uk/journalsPermissions.nav |
DOI: | 10.1177/1747493018778113 |
Grant ID: | http://purl.org/au-research/grants/nhmrc/565402 http://purl.org/au-research/grants/nhmrc/1042600 |
Published version: | http://dx.doi.org/10.1177/1747493018778113 |
Appears in Collections: | Aurora harvest 8 Medicine publications |
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