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Type: Journal article
Title: Advances in imaging specific mediators of inflammatory bowel disease
Author: Dmochowska, N.
Wardill, H.
Hughes, P.
Citation: International Journal of Molecular Sciences, 2018; 19(9):2471-1-2471-13
Publisher: MDPI AG
Issue Date: 2018
ISSN: 1661-6596
Statement of
Nicole Dmochowska, Hannah R. Wardill and Patrick A. Hughes
Abstract: Inflammatory bowel disease (IBD) is characterized by chronic remitting and relapsing inflammation of the lower gastrointestinal tract. The etiology underlying IBD remains unknown, but it is thought to involve a hypersensitive immune response to environmental antigens, including the microbiota. Diagnosis and monitoring of IBD is heavily reliant on endoscopy, which is invasive and does not provide information regarding specific mediators. This review describes recent developments in imaging of IBD with a focus on positron emission tomography (PET) and single-photon emission computed tomography (SPECT) of inflammatory mediators, and how these developments may be applied to the microbiota.
Keywords: Inflammatory Bowel Disease (IBD); colitis; PET; SPECT; microbiota; cytokine; chemokine; inflammation
Description: Published: 21 August 2018
Rights: © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (
RMID: 0030097239
DOI: 10.3390/ijms19092471
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Appears in Collections:Medicine publications

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