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Type: Journal article
Title: Interacting effects of land use and climate on rodent-borne pathogens in central Kenya
Author: Young, H.
McCauley, D.
Dirzo, R.
Nunn, C.
Campana, M.
Agwanda, B.
Otarola-Castillo, E.
Castillo, E.
Pringle, R.
Veblen, K.
Salkeld, D.
Stewardson, K.
Fleischer, R.
Lambin, E.
Palmer, T.
Helgen, K.
Citation: Philosophical Transactions of the Royal Society B: Biological Sciences, 2017; 372(1722):20160116-1-20160116-11
Publisher: The Royal Society
Issue Date: 2017
ISSN: 0962-8436
Statement of
Hillary S. Young, Douglas J. McCauley, Rodolfo Dirzo, Charles L. Nunn, Michael G. Campana, Bernard Agwanda, Erik R. Otarola-Castillo, Eric R. Castillo, Robert M. Pringle, Kari E. Veblen, Daniel J. Salkeld, Kristin Stewardson, Robert Fleischer, Eric F. Lambin, Todd M. Palmer and Kristofer M. Helgen
Abstract: Understanding the effects of anthropogenic disturbance on zoonotic disease risk is both a critical conservation objective and a public health priority. Here, we evaluate the effects of multiple forms of anthropogenic disturbance across a precipitation gradient on the abundance of pathogen-infected small mammal hosts in a multi-host, multi-pathogen system in central Kenya. Our results suggest that conversion to cropland and wildlife loss alone drive systematic increases in rodent-borne pathogen prevalence, but that pastoral conversion has no such systematic effects. The effects are most likely explained both by changes in total small mammal abundance, and by changes in relative abundance of a few high-competence species, although changes in vector assemblages may also be involved. Several pathogens responded to interactions between disturbance type and climatic conditions, suggesting the potential for synergistic effects of anthropogenic disturbance and climate change on the distribution of disease risk. Overall, these results indicate that conservation can be an effective tool for reducing abundance of rodent-borne pathogens in some contexts (e.g. wildlife loss alone); however, given the strong variation in effects across disturbance types, pathogen taxa and environmental conditions, the use of conservation as public health interventions will need to be carefully tailored to specific pathogens and human contexts.This article is part of the themed issue 'Conservation, biodiversity and infectious disease: scientific evidence and policy implications'.
Keywords: Disease; diversity; dilution effect; susceptible host regulation, landscape ecology; land-use change
Rights: © 2017 The Authors. Published by the Royal Society under the terms of the Creative Commons Attribution License, which permits unrestricted use, provided the original author and source are credited.
RMID: 0030070178
DOI: 10.1098/rstb.2016.0116
Appears in Collections:Public Health publications

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