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|Title:||Distribution of two hemolytic toxin genes in clinical and environmental isolates of Aeromonas spp.: correlation with virulence in a suckling mouse model|
|Citation:||FEMS Microbiology Letters, 1999; 174(1):131-136|
|Publisher:||Oxford University Press (OUP)|
|Abstract:||Previous studies have shown that two hemolytic toxins, HlyA and AerA, contribute to the virulence of Aeromonas hydrophila. A survey was performed to gauge the distribution of hlyA and aerA genes in clinical and environmental Aeromonas isolates. For A. hydrophila, A. veronii biotype sobria and A caviae, 96%, 12% and 35% of strains, respectively, were hlyA positive, whereas, 78%, 97%, 41%, respectively, were aerA positive. All virulent A. hydrophila isolates were hlyA+ aerA+. This genotype was most common in A. hydrophila (75.4%) followed by A. caviae (29.4%) and A. veronii biotype sobria (9.6%). For A. hydrophila, a two-hemolytic toxin model of virulence provides the best prediction of virulence in an animal model.|
Gram-Negative Bacterial Infections
Escherichia coli Proteins
Polymerase Chain Reaction
Pore Forming Cytotoxic Proteins
|Appears in Collections:||Aurora harvest 2|
Microbiology and Immunology publications
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