Please use this identifier to cite or link to this item:
Scopus Web of ScienceĀ® Altmetric
Type: Journal article
Title: Distribution of two hemolytic toxin genes in clinical and environmental isolates of Aeromonas spp.: correlation with virulence in a suckling mouse model
Author: Heuzenroeder, M.
Wong, C.
Flower, R.
Citation: FEMS Microbiology Letters, 1999; 174(1):131-136
Publisher: Oxford University Press (OUP)
Issue Date: 1999
ISSN: 0378-1097
Abstract: Previous studies have shown that two hemolytic toxins, HlyA and AerA, contribute to the virulence of Aeromonas hydrophila. A survey was performed to gauge the distribution of hlyA and aerA genes in clinical and environmental Aeromonas isolates. For A. hydrophila, A. veronii biotype sobria and A caviae, 96%, 12% and 35% of strains, respectively, were hlyA positive, whereas, 78%, 97%, 41%, respectively, were aerA positive. All virulent A. hydrophila isolates were hlyA+ aerA+. This genotype was most common in A. hydrophila (75.4%) followed by A. caviae (29.4%) and A. veronii biotype sobria (9.6%). For A. hydrophila, a two-hemolytic toxin model of virulence provides the best prediction of virulence in an animal model.
Keywords: Vero Cells
Animals, Suckling
Gram-Negative Bacterial Infections
Bacterial Proteins
Escherichia coli Proteins
Bacterial Toxins
Blotting, Southern
Polymerase Chain Reaction
Toxicity Tests
Environmental Microbiology
Gene Frequency
Genes, Bacterial
Pore Forming Cytotoxic Proteins
Hemolysin Proteins
Chlorocebus aethiops
DOI: 10.1016/S0378-1097(99)00130-5
Appears in Collections:Aurora harvest 2
Microbiology and Immunology publications

Files in This Item:
There are no files associated with this item.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.