Please use this identifier to cite or link to this item:
Scopus Web of Science® Altmetric
Type: Journal article
Title: A review of tooth discoloration after regenerative endodontic therapy
Author: Kahler, B.
Rossi-Fedele, G.
Citation: Journal of Endodontics, 2016; 42(4):563-569
Publisher: Elsevier
Issue Date: 2016
ISSN: 0099-2399
Statement of
Bill Kahler, Giampiero Rossi-Fedele
Abstract: Introduction: The American Association of Endodontists clinical considerations for regenerative therapy (April 2015) advise of the risk of the possible adverse effect of staining of teeth. It is widely acknowledged that before these guidelines were developed there was no standardized protocol for regenerative therapy, and different approaches using different materials have been reported. The purpose of this review was to undertake a systematic review of published cases to determine the incidence of reported discoloration and examine whether there was any particular association with any material. Methods: A PubMed search was performed using key words for regenerative endodontic therapy consistent with prior published systematic reviews. Results There were 80 studies identified with 379 teeth treated. Many of the studies did not report on the presence or absence of discoloration. It was noted that there was a strong association of discoloration with the use of triple antibiotic paste containing minocycline; however, discoloration was also noted when other materials were used. Unfortunately, bleaching of stained teeth was not predictably achieved in some studies. Conclusions: The use of triple antibiotic paste with minocycline as the intracanal medicament should be reconsidered. Either calcium hydroxide or the double antibiotic paste of metronidazole and ciprofloxacin may limit discoloration. Mineral trioxide aggregate was also associated with discoloration. However, there is little evidence of an alternative superior material as a coronal barrier. Because discoloration is a patient-orientated outcome, further research should document and identify the incidence of discoloration in regenerative endodontic treatment.
Keywords: Discoloration; mineral trioxide aggregate; minocycline; regenerative endodontic therapy; revascularization; revitalization; triple antibiotic paste
Rights: © 2016 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.
DOI: 10.1016/j.joen.2015.12.022
Published version:
Appears in Collections:Aurora harvest 3
Dentistry publications

Files in This Item:
There are no files associated with this item.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.