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https://hdl.handle.net/2440/117277
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DC Field | Value | Language |
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dc.contributor.author | Wijs, L. | - |
dc.contributor.author | de Graaff, E. | - |
dc.contributor.author | Leemaqz, S. | - |
dc.contributor.author | Dekker, G. | - |
dc.date.issued | 2017 | - |
dc.identifier.citation | The Journal of Maternal-Fetal and Neonatal Medicine, 2017; 30(23):2851-2857 | - |
dc.identifier.issn | 1476-4954 | - |
dc.identifier.issn | 1476-4954 | - |
dc.identifier.uri | http://hdl.handle.net/2440/117277 | - |
dc.description.abstract | Introduction: The aim of this paper was to provide an in-depth analysis of all stillbirth causation over a period of 10 years in a busy maternity unit located in a socioeconomically disadvantaged urban area, with an emphasis on overlapping pathology. Materials and methods: A retrospective analysis of all structurally normal stillbirths in singleton pregnancies born during 2002–2012. The PSANZ stillbirth classification was used; per stillbirth subgroup main risk factors were evaluated. Results: Out of 130 cases, 43% showed overlapping pathologies. In the remaining 74 (56%) cases, the following single pathologies were found: IUGR 20 (15%), infection 12 (9%), abruption 8 (6%), placental thrombotic pathology 8 (6%), miscellaneous 6 stillbirths (5%), and 20 cases (15%) unexplained. Smoking was a risk factor for stillbirth associated with abruption (OR 3.639), infection (OR 2.271), and thrombotic pathology (OR 2.168). Drug use had an association with (placental) infection (OR 3.598). Obesity showed a significant association with IUGR (OR 3.782) and abruption (OR 9.040). Thrombophilia risk analysis for the overall group of stillbirths showed significant results for Protein S (OR 8.889) and homocysteine >90th centile (OR 2.087). Conclusions: Overlapping pathology was identified in 43% of stillbirths. Infection, IUGR, and abruption were the most important single cause of stillbirth. | - |
dc.description.statementofresponsibility | Laura Anna Wijs, Esti Charlotte de Graaff, Shalem Leemaqz and Gustaaf Dekker | - |
dc.language.iso | en | - |
dc.publisher | Taylor & Francis | - |
dc.rights | © 2016 Informa UK Limited, trading as Taylor & Francis Group | - |
dc.source.uri | http://dx.doi.org/10.1080/14767058.2016.1265933 | - |
dc.subject | Australia | - |
dc.subject | Stillbirth | - |
dc.subject | causes | - |
dc.title | Causes of stillbirth in a socioeconomically disadvantaged urban Australian population - a comprehensive analysis | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1080/14767058.2016.1265933 | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Leemaqz, S. [0000-0003-4616-8426] | - |
dc.identifier.orcid | Dekker, G. [0000-0002-7362-6683] | - |
Appears in Collections: | Aurora harvest 3 Paediatrics publications |
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