Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/117404
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Type: | Journal article |
Title: | Perspective: biomedical sensing and imaging with optical fibers - innovation through convergence of science disciplines |
Author: | Li, J. Ebendorff-Heidepriem, H. Gibson, B. Greentree, A.D. Hutchinson, M. Jia, P. Kostecki, R. Liu, G. Orth, A. Ploschner, M. Schartner, E.P. Warren-Smith, S.C. Zhang, K. Tsiminis, G. Goldys, E.M. |
Citation: | APL Photonics, 2018; 3(10):1-20 |
Publisher: | AIP Publishing |
Issue Date: | 2018 |
ISSN: | 2378-0967 2378-0967 |
Statement of Responsibility: | Jiawen Li ... Heike Ebendorff-Heidepriem ... Mark R. Hutchinson ... Roman Kostecki ... Erik P. Schartner ... Georgios Tsiminis ... Stephen C. Warren-Smith ... et al. |
Abstract: | The probing of physiological processes in living organisms is a grand challenge that requires bespoke analytical tools. Optical fiber probes offer a minimally invasive approach to report physiological signals from specific locations inside the body. This perspective article discusses a wide range of such fiber probes developed at the Australian Research Council Centre of Excellence for Nanoscale BioPhotonics. Our fiber platforms use a range of sensing modalities, including embedded nanodiamonds for magnetometry, interferometric fiber cavities for refractive index sensing, and tailored metal coatings for surface plasmon resonance sensing. Other fiber probes exploit molecularly sensitive Raman scattering or fluorescence where optical fibers have been combined with chemical and immunosensors. Fiber imaging probes based on interferometry and computational imaging are also discussed as emerging in vivo diagnostic devices. We provide examples to illustrate how the convergence of multiple scientific disciplines generates opportunities for the fiber probes to address key challenges in real-time in vivo diagnostics. These future fiber probes will enable the asking and answering of scientific questions that were never possible before. |
Rights: | © 2018 Author(s). All article content, except where otherwise noted, is licensed under a Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/) |
DOI: | 10.1063/1.5040861 |
Grant ID: | http://purl.org/au-research/grants/arc/FT160100357 http://purl.org/au-research/grants/arc/CE140100003 |
Published version: | http://dx.doi.org/10.1063/1.5040861 |
Appears in Collections: | Aurora harvest 8 Medicine publications |
Files in This Item:
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hdl_117404.pdf | Published version | 6.89 MB | Adobe PDF | View/Open |
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