Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/117560
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dc.contributor.author | Wang, L. | - |
dc.contributor.author | Dong, J. | - |
dc.contributor.author | Xian, C.J. | - |
dc.date.issued | 2015 | - |
dc.identifier.citation | BioMed Research International, 2015; 2015:376474-1-376474-14 | - |
dc.identifier.issn | 2314-6133 | - |
dc.identifier.issn | 2314-6141 | - |
dc.identifier.uri | http://hdl.handle.net/2440/117560 | - |
dc.description.abstract | Osteocytes, the major type of bone cells which reside in their lacunar and canalicular system within the bone matrix, function as biomechanosensors and biomechanotransducers of the bone. Although biomechanical behaviour of the osteocyte-lacunar-canalicular system has been investigated in previous studies mostly using computational 2-dimensional (2D) geometric models, only a few studies have used the 3-dimensional (3D) finite element (FE) model. In the current study, a 3D FE model was used to predict the responses of strain distributions of osteocyte-lacunar-canalicular system analyzed under static and cyclic loads. The strain amplification factor was calculated for all simulations. Effects on the strain of the osteocyte system were investigated under 500, 1500, 2000, and 3000 microstrain loading magnitudes and 1, 5, 10, 40, and 100 Hz loading frequencies. The maximum strain was found to change with loading magnitude and frequency. It was observed that maximum strain under 3000-microstrain loading was higher than those under 500, 1500, and 2000 microstrains. When the loading strain reached the maximum magnitude, the strain amplification factor of 100 Hz was higher than those of the other frequencies. Data from this 3D FE model study suggests that the strain amplification factor of the osteocyte-lacunar-canalicular system increases with loading frequency and loading strain increasing. | - |
dc.description.statementofresponsibility | Liping Wang, Jianghui Dong and Cory J. Xian | - |
dc.language.iso | en | - |
dc.publisher | Hindawi | - |
dc.rights | © 2015 Liping Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | - |
dc.source.uri | http://dx.doi.org/10.1155/2015/376474 | - |
dc.subject | Osteocytes | - |
dc.title | Strain amplification analysis of an osteocyte under static and cyclic loading: a finite element study | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1155/2015/376474 | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Xian, C.J. [0000-0002-8467-2845] | - |
Appears in Collections: | Aurora harvest 3 Medicine publications |
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File | Description | Size | Format | |
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hdl_117560.pdf | Published version | 3.78 MB | Adobe PDF | View/Open |
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