Please use this identifier to cite or link to this item:
Scopus Web of Science® Altmetric
Type: Journal article
Title: International Clinical Practice Guidelines for Sarcopenia (ICFSR): screening, diagnosis and management
Author: Dent, E.
Morley, J.E.
Cruz-Jentoft, A.J.
Arai, H.
Kritchevsky, S.B.
Guralnik, J.
Bauer, J.M.
Pahor, M.
Clark, B.C.
Cesari, M.
Ruiz, J.
Sieber, C.C.
Aubertin-Leheudre, M.
Waters, D.L.
Visvanathan, R.
Landi, F.
Villareal, D.T.
Fielding, R.
Won, C.W.
Theou, O.
et al.
Citation: Journal of Nutrition, Health and Aging, 2018; 22(10):1148-1161
Publisher: Springer
Issue Date: 2018
ISSN: 1279-7707
Statement of
Elsa Dent, J. E. Morley, A. J. Cruz-Jentoft, H. Arai, S. B. Kritchevsky ... O. Theou .... et al.
Abstract: OBJECTIVES:Sarcopenia, defined as an age-associated loss of skeletal muscle function and muscle mass, occurs in approximately 6 - 22 % of older adults. This paper presents evidence-based clinical practice guidelines for screening, diagnosis and management of sarcopenia from the task force of the International Conference on Sarcopenia and Frailty Research (ICSFR). METHODS:To develop the guidelines, we drew upon the best available evidence from two systematic reviews paired with consensus statements by international working groups on sarcopenia. Eight topics were selected for the recommendations: (i) defining sarcopenia; (ii) screening and diagnosis; (iii) physical activity prescription; (iv) protein supplementation; (v) vitamin D supplementation; (vi) anabolic hormone prescription; (vii) medications under development; and (viii) research. The ICSFR task force evaluated the evidence behind each topic including the quality of evidence, the benefit-harm balance of treatment, patient preferences/values, and cost-effectiveness. Recommendations were graded as either strong or conditional (weak) as per the GRADE (Grading of Recommendations Assessment, Development and Evaluation) approach. Consensus was achieved via one face-to-face workshop and a modified Delphi process. RECOMMENDATIONS:We make a conditional recommendation for the use of an internationally accepted measurement tool for the diagnosis of sarcopenia including the EWGSOP and FNIH definitions, and advocate for rapid screening using gait speed or the SARC-F. To treat sarcopenia, we strongly recommend the prescription of resistance-based physical activity, and conditionally recommend protein supplementation/a protein-rich diet. No recommendation is given for Vitamin D supplementation or for anabolic hormone prescription. There is a lack of robust evidence to assess the strength of other treatment options.
Keywords: 80 and over
Sarcopenia diagnosis
muscle strength
practice guideline
sarcopenia therapy
Rights: © Serdi and Springer-Verlag International SAS, part of Springer Nature
DOI: 10.1007/s12603-018-1139-9
Grant ID:
Appears in Collections:Aurora harvest 8
Public Health publications

Files in This Item:
There are no files associated with this item.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.