Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/11819
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dc.contributor.authorRobinson, J.en
dc.contributor.authorMoore, V.en
dc.contributor.authorOwens, J.en
dc.contributor.authorMcMillen, I.en
dc.date.issued2000en
dc.identifier.citationEuropean Journal of Obstetrics Gynecology and Reproductive Biology, 2000; 92(1):13-19en
dc.identifier.issn0301-2115en
dc.identifier.issn1872-7654en
dc.identifier.urihttp://hdl.handle.net/2440/11819-
dc.description.abstractRegulation of growth of the fetus and its placenta begins before pregnancy. Early in pregnancy the mother sets the rate of growth of the fetus on a trajectory, which may be modified by events later in pregnancy. Low maternal weight for height, history of previous small babies, maternal undernutrition, pregnancy disorders, e.g. pre-eclampsia, are associated with low birthweight. Maternal smoking is a major factor in developed countries; infections and undernutrition in developing countries.Recently, there has been emphasis on adverse long-term outcomes including ischaemic heart disease, hypertension and diabetes associated with poor fetal growth. Experimental studies in animals show that some of these outcomes can readily be induced by restriction of fetal growth. Progress in determining successful treatments to improve the growth of the fetus has lagged behind these epidemiological and experimental findings. However, nutrient supplements improve growth in undernourished women and smoking cessation also improves fetal size and outcome.en
dc.language.isoenen
dc.publisherElsevier Sci Ireland Ltden
dc.rightsCopyright © 2000 Elsevier Science Ireland Ltd. All rights reserved.en
dc.subjectCauses; Fetal growth restriction; Long-term outcomes; Nutrient supplements; Smokingen
dc.titleOrigins of fetal growth restrictionen
dc.typeJournal articleen
dc.identifier.rmid0001001671en
dc.identifier.doi10.1016/S0301-2115(00)00421-8en
dc.identifier.pubid63083-
pubs.library.collectionPhysiology publicationsen
pubs.verification-statusVerifieden
pubs.publication-statusPublisheden
dc.identifier.orcidRobinson, J. [0000-0002-4515-6039]en
dc.identifier.orcidMoore, V. [0000-0001-9505-6450]en
dc.identifier.orcidOwens, J. [0000-0002-7498-1353]en
Appears in Collections:Physiology publications

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