Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/118884
Type: Journal article
Title: Obesity and polycystic ovary syndrome
Author: Naderpoor, N.
Shorakae, S.
Joham, A.
Boyle, J.
De Courten, B.
Teede, H.
Citation: Minerva endocrinologica, 2015; 40(1):37-51
Publisher: Minerva Medica
Issue Date: 2015
ISSN: 0391-1977
1827-1634
Statement of
Responsibility: 
N. Naderpoor, S. Shorakae, A. Joham, J. Boyle, B. De Courten, H. J. Teede
Abstract: Obesity is now a major international health concern. It is increasingly common in young women with reproductive, metabolic and psychological health impacts. Reproductive health impacts are often poorly appreciated and include polycystic ovary syndrome (PCOS), infertility and pregnancy complications. PCOS is the most common endocrine condition in women and is underpinned by hormonal disturbances including insulin resistance and hyperandrogenism. Obesity exacerbates hormonal and clinical features of PCOS and women with PCOS appear at higher risk of obesity, with multiple underlying mechanisms linking the conditions. Lifestyle intervention is first line in management of PCOS to both prevent weight gain and induce weight loss; however improved engagement and sustainability remain challenges with the need for more research. Medications like metformin, orlistat, GLP1 agonists and bariatric surgery have been used with the need for large scale randomised clinical trials to define their roles.
Keywords: Obesity, Abdominal
Rights: © 2015 EDIZIONI MINERVA MEDICA
RMID: 0030094765
Appears in Collections:Medicine publications

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