Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/119172
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Type: Journal article
Title: Trefoil factor family: unresolved questions and clinical perspectives
Author: Braga Emidio, N.
Hoffmann, W.
Brierley, S.
Muttenthaler, M.
Citation: Trends in Biochemical Sciences, 2019; 44(5):387-390
Publisher: Elsevier
Issue Date: 2019
ISSN: 0968-0004
1362-4326
Statement of
Responsibility: 
Nayara Braga Emidio, Werner Hoffmann, Stuart M.Brierley, Markus Muttenthaler
Abstract: The trefoil factor family of peptides (TFF1, TFF2, TFF3) with their lectin activities play important roles in mucosal protection and repair. However, major gaps in understanding their molecular function have hampered therapeutic development for gastrointestinal disorders. We provide here a critical overview of the status quo.
Keywords: cell migration
gastrointestinal wound healing
lectin
mucins
mucosal protection
mucositis
Rights: © 2019 Elsevier Ltd. All rights reserved.
DOI: 10.1016/j.tibs.2019.01.004
Grant ID: http://purl.org/au-research/grants/arc/DE150100784
http://purl.org/au-research/grants/nhmrc/1126378
http://purl.org/au-research/grants/nhmrc/1083480
http://purl.org/au-research/grants/nhmrc/1139366
http://purl.org/au-research/grants/nhmrc/1140297
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