Adelaide Research & Scholarship
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https://hdl.handle.net/2440/119172
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| Type: | Journal article |
| Title: | Trefoil factor family: unresolved questions and clinical perspectives |
| Author: | Braga Emidio, N. Hoffmann, W. Brierley, S. Muttenthaler, M. |
| Citation: | Trends in Biochemical Sciences, 2019; 44(5):387-390 |
| Publisher: | Elsevier |
| Issue Date: | 2019 |
| ISSN: | 0968-0004 1362-4326 |
| Statement of Responsibility: | Nayara Braga Emidio, Werner Hoffmann, Stuart M.Brierley, Markus Muttenthaler |
| Abstract: | The trefoil factor family of peptides (TFF1, TFF2, TFF3) with their lectin activities play important roles in mucosal protection and repair. However, major gaps in understanding their molecular function have hampered therapeutic development for gastrointestinal disorders. We provide here a critical overview of the status quo. |
| Keywords: | cell migration gastrointestinal wound healing lectin mucins mucosal protection mucositis |
| Rights: | © 2019 Elsevier Ltd. All rights reserved. |
| DOI: | 10.1016/j.tibs.2019.01.004 |
| Grant ID: | http://purl.org/au-research/grants/arc/DE150100784 http://purl.org/au-research/grants/nhmrc/1126378 http://purl.org/au-research/grants/nhmrc/1083480 http://purl.org/au-research/grants/nhmrc/1139366 http://purl.org/au-research/grants/nhmrc/1140297 |
| Appears in Collections: | Aurora harvest 8 Medicine publications |
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