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Type: Journal article
Title: Palaeopathology of the earlobe crease (Frank's sign): new insights from Renaissance art
Author: Galassi, F.
Borghi, C.
Ballestriero, R.
Habicht, M.
Henneberg, M.
Rühli, F.
Citation: International Journal of Cardiology, 2017; 236:82-84
Publisher: Elsevier
Issue Date: 2017
ISSN: 0167-5273
Statement of
Francesco M. Galassi, Claudio Borghi, Roberta Ballestriero, Michael E. Habicht, Maciej Henneberg, Frank J. Rühli
Abstract: Several studies have associated the earlobe crease sign, discovered by Sanders T. Frank in 1973, with cardiovascular pathology, yet very few studies have focused on the antiquity of this trait, with the most ancient one thought to date back to the Roman Emperor Hadrian (76-138CE). This article presents two more cases from the Italian Renaissance in the works of the artist Andrea Mantegna (1431-1506) and examines them in a multidisciplinary fashion.
Keywords: Frank's sign; earlobe crease; cardiovascular pathology; prevention; palaeopathology; Mantegna; Renaissance
Rights: © 2017 Elsevier B.V. All rights reserved.
DOI: 10.1016/j.ijcard.2017.02.128
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