Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/119870
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Type: Journal article
Title: A comparison of early versus delayed elective electrical cardioversion for recurrent episodes of persistent atrial fibrillation: a multi-center study
Author: Voskoboinik, A.
Kalman, E.
Plunkett, G.
Knott, J.
Moskovitch, J.
Sanders, P.
Kistler, P.
Kalman, J.
Citation: International Journal of Cardiology, 2019; 284:33-37
Publisher: Elsevier
Issue Date: 2019
ISSN: 0167-5273
1874-1754
Statement of
Responsibility: 
Aleksandr Voskoboinik, Elana Kalman, George Plunkett, Jonathan Knott, Jeremy Moskovitch, Prashanthan Sanders, Peter M. Kistler, Jonathan M. Kalman
Abstract: BACKGROUND:Due to barriers to accessing timely elective electrical cardioversion (CV) for persistent AF (PeAF), we adopted a policy of instructing patients to present directly to the Emergency Department (ED) for CV. OBJECTIVE:We compare a strategy of Emergency CV (ED-CV) versus Elective CV (EL-CV) for treatment of symptomatic PeAF. METHODS:Between 2014 and 7, we evaluated 150 patients undergoing CV for PeAF. ED-CV patients were provided an AF action plan for recurrent symptoms and advised to present to ED within 36 h. EL-CV patients followed standard care, including cardiologist referral and placement on an elective hospital waiting list. Follow-up was 12 months. RESULTS:We included 75 consecutive ED-CV patients and 75 consecutive EL-CV patients. ED-CV patients had a significantly shorter median AF duration prior to CV (1 day vs 3 months; p < 0.01) and less overall AF-related symptoms at 12 months (modified EHRA symptom score ≥ 2a in 44% vs 72%; p = 0.005). Time to next AF recurrence was longer in the ED-CV group (295 ± 15 vs 245 ± 15 days; logrank p = 0.001), as was time to AF ablation referral (314 ± 13 vs 276 ± 15 days; logrank p = 0.01). Baseline LA area was similar (ED-CV 27 ± 4 cm2 vs EL-CV 28 ± 11 cm2; p = 0.67), however EL-CV had larger atria at follow-up (31 ± 8 vs 26 ± 6 cm2; p = 0.01). There were no complications in either group. CONCLUSION:ED-CV is an acceptable strategy for symptomatic PeAF. In addition to reduced time spent in AF and improved symptom scores, this strategy may also slow progression of atrial substrate & delay onset of next AF episode.
Keywords: Atrial fibrillation; Atrial remodelling; Electrical cardioversion; Left atrium
Rights: © 2018 Published by Elsevier B.V.
RMID: 0030102596
DOI: 10.1016/j.ijcard.2018.10.068
Appears in Collections:Medicine publications

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