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Type: Journal article
Title: Lethal dengue virus infection: a forensic overview
Author: Byard, R.
Citation: American Journal of Forensic Medicine and Pathology, 2016; 37(2):74-78
Publisher: Wolters Kluwer
Issue Date: 2016
ISSN: 0195-7910
Statement of
Roger W. Byard
Abstract: Dengue virus is a single-stranded RNA virus that is a member of the family Flaviviridae, genus Flavivirus. It is usually transmitted by the female Aedes aegypti mosquito. Dengue fever is a febrile illness caused by 1 of 4 serotypes of the virus, which may progress to dengue hemorrhagic fever or dengue shock syndrome. The mortality rate of untreated dengue shock syndrome is more than 20%. The reported incidence has increased 30-fold for the past 50 years with an estimated 50 to 100 million dengue infections globally each year, which includes 22,000 deaths. Because of this rapid increase in numbers, more cases will be seen in forensic mortuaries, with diagnostic problems arising from nonspecific or unusual manifestations. In this review, the clinicopathological features of dengue viral infection are evaluated. Adequate blood and tissue sampling at the time of autopsy is mandatory for successful microbiological identification and characterization.
Keywords: Dengue hemorrhagic fever; dengue shock syndrome; vector; Aedes mosquito; shock; sudden death
Rights: © 2016 Wolters Kluwer Health, Inc. All rights reserved.
RMID: 0030046768
DOI: 10.1097/PAF.0000000000000236
Appears in Collections:Medicine publications

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