Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/120649
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Type: Journal article
Title: Home-based education and learning program for atrial fibrillation: rationale and design of the HELP-AF study
Author: Hendriks, J.
Brooks, A.
Rowett, D.
Moss, J.
Gallagher, C.
Nyfort-Hansen, K.
Simmons, S.
Middeldorp, M.
Jones, T.
Thomas, G.
Lau, D.
Sanders, P.
Citation: Canadian Journal of Cardiology, 2019; 35(7):846-854
Publisher: Elsevier
Issue Date: 2019
ISSN: 0828-282X
1916-7075
Statement of
Responsibility: 
Jeroen M. Hendriks, Anthony G. Brooks, Debra Rowett, John R. Moss, Celine Gallagher, Karin Nyfort-Hansen, Shalini Simmons, Melissa E. Middeldorp, Tina Jones, Gijo Thomas, Dennis H. Lau and Prashanthan Sanders
Abstract: BACKGROUND:Atrial fibrillation (AF) is a growing global epidemic, with its prevalence expected to significantly rise over coming decades. AF poses a substantial burden on health care systems, largely due to hospitalizations. Home-based clinical characterization has demonstrated improved outcomes in cardiac populations, but its impact on AF remains poorly defined. To test this hypothesis in AF, we developed the Home-Based Education and Learning Program for Patients With Atrial Fibrillation (HELP-AF) study. METHODS:The HELP-AF study is a prospective multicentre randomized controlled trial that will recruit 620 patients presenting to hospital emergency departments (EDs) with symptomatic AF (ANZCTR Registration: ACTRN12611000607976). Patients will be randomized to either the HELP-AF intervention or usual care. The intervention consists of 2 home visits by a nurse or pharmacist trained in the structured educational visiting (SEV) method. Patients in the control group will receive usual discharge follow-up care. RESULTS:The primary endpoints are total unplanned hospital admissions and quality of life. Secondary endpoints include AF symptom severity and burden score; time to first hospital admission; total unplanned days in hospital; total AF-related hospital admissions (including atrial flutter); total cardiac and noncardiac hospital admissions; total AF- or atrial flutter-related; cardiac- and noncardiac-related ED presentations; and all-cause mortality. An economic evaluation will also be performed. Clinical endpoints will be adjudicated by independent blinded assessors. Follow-up will be at 24 months. CONCLUSIONS:This study will assess the efficacy of a home-based structured patient-centred educational intervention in patients with AF.
Keywords: Humans
Atrial Fibrillation
Patient Admission
Prospective Studies
Quality of Life
Emergency Service, Hospital
Home Care Services, Hospital-Based
Patient Education as Topic
Multicenter Studies as Topic
Randomized Controlled Trials as Topic
Rights: Crown Copyright © 2019 Published by Elsevier Inc. on behalf of the Canadian Cardiovascular Society. All rights reserved
DOI: 10.1016/j.cjca.2019.03.020
Appears in Collections:Aurora harvest 4
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