Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/120678
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Type: Journal article
Title: In overweight and obese women, fetal ultrasound biometry accurately predicts newborn measures
Author: O'Brien, C.
Louise, J.
Deussen, A.
Dodd, J.
Citation: Australian and New Zealand Journal of Obstetrics and Gynaecology, 2019; OnlinePubl:1-7
Publisher: Wiley
Issue Date: 2019
ISSN: 0004-8666
1479-828X
Statement of
Responsibility: 
Cecelia M. O'Brien, Jennie Louise, Andrea Deussen, Jodie M. Dodd
Abstract: INTRODUCTION:The aim of this study was to evaluate the association between fetal ultrasound and newborn biometry and adiposity measures in the setting of maternal obesity. MATERIAL AND METHODS:The study population involved 845 overweight or obese pregnant women, who participated in the Standard Care Group of the LIMIT randomised trial (ACTRN12607000161426, 9/03/2007). At 36 weeks gestation, fetal biometry, estimated fetal weight (EFW) and adiposity measures including mid-thigh fat mass (MTFM), subscapular fat mass (SSFM), and abdominal fat mass (AFM) were undertaken using ultrasound. Neonatal anthropometric measurements obtained after birth included birthweight, head circumference (HC), abdominal circumference (AC) and skinfold thickness measurements (SFTM) of the subscapular region and abdomen. RESULTS:At 36 weeks gestation, every 1 g increase in EFW was associated with a 0.94 g increase in birthweight (95% CI 0.88-0.99; P < 0.001). For every 1 mm increase in the fetal ultrasound measure, there was a 0.69 mm increase in birth HC (95% CI 0.63-0.75, P < 0.001) and 0.69 mm increase in birth AC (95% CI 0.60-0.79, P < 0.001). Subscapular fat mass in the fetus and the newborn (0.29 mm, 95% CI 0.20-0.39, P < 0.001) were moderately associated, but AFM measurements were not (0.06 mm, -0.03 to 0.15, P = 0.203). There is no evidence that these relationships differed by maternal body mass index. CONCLUSION:In women who are overweight or obese, fetal ultrasound accurately predicts neonatal HC and AC along with birthweight.
Keywords: adiposity; birthweight; fetal body composition; obesity; pregnancy
Rights: © 2019 The Royal Australian and New Zealand College of Obstetricians and Gynaecologists
RMID: 0030120687
DOI: 10.1111/ajo.13025
Grant ID: http://purl.org/au-research/grants/nhmrc/627005
Appears in Collections:Paediatrics publications

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