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Type: Journal article
Title: Renal-limited thrombotic microangiopathy and acute interstitial nephritis with a single dose of quinine
Author: Anjelo, J.
Rao, N.
David, V.G.
Otto, S.
Russ, G.
Citation: Clinical Kidney Journal, 2014; 7(3):311-313
Publisher: Oxford University Press
Issue Date: 2014
ISSN: 2048-8505
Statement of
Jobert Anjelo, Nitesh Rao, Vinoi G. David, Sophia Otto, Graeme Russ
Abstract: Quinine has been reported to cause acute kidney injury by various mechanisms. The response to quinine can result in a spectrum of problems ranging from isolated thrombocytopenia to thrombotic microangiopathy (TMA) to disseminated intravascular coagulation. Quinine has also been reported to cause acute interstitial nephritis (AIN). We report an unusual presentation where both of these entities of renal-limited TMA and AIN were precipitated by a single dose of quinine.
Keywords: acute renal failure
interstitial nephritis
thrombotic microangiopathy
Rights: © The Author 2014. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved.
DOI: 10.1093/ckj/sfu035
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