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Type: Journal article
Title: Adherence to oral cancer therapy in older adults: The International Society of Geriatric Oncology (SIOG) taskforce recommendations
Author: Mislang, A.R.
Wildes, T.M.
Kanesvaran, R.
Baldini, C.
Holmes, H.M.
Nightingale, G.
Coolbrandt, A.
Biganzoli, L.
Citation: Cancer Treatment Reviews, 2017; 57:58-66
Publisher: Elsevier
Issue Date: 2017
ISSN: 0305-7372
Statement of
Anna Rachelle Mislang, Tanya M. Wildes, Ravindran Kanesvaran, Capucine Baldini, Holly M. Holmes, Ginah Nightingale, Annemarie Coolbrandt, Laura Biganzoli
Abstract: There is an increasing trend towards using oral systemic therapy in patients with cancer. Compared to parenteral therapy, oral cancer agents offer convenience, have similar efficacy, and are preferred by patients, consequently making its use appealing in older adults. However, adherence is required to ensure its efficacy and to avoid compromising treatment outcomes, especially when the treatment goal is curative, or in case of symptomatic/rapidly progressing disease, where dose-intensity is important. This opens a new challenge for clinicians, as optimizing patient adherence is challenging, particularly due to lack of consensus and scarcity of available clinical evidence. This manuscript aims to review the impact of age-related factors on adherence, summarize the evidence on adherence, recommend methods for selecting patients suitable for oral cancer agents, and advise monitoring interventions to promote adherence to treatment.
Keywords: Adherence; Geriatric oncology; Oral cancer agents; Toxicity
Rights: © 2017 Published by Elsevier Ltd.
RMID: 0030085707
DOI: 10.1016/j.ctrv.2017.05.002
Appears in Collections:Medicine publications

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